In the conference room, Fang Datuo said nothing, pushed the MRI map and various substance level data in front of Chu Yu, turned on the computer, and some dynamic images needed to be projected on the screen.
Chu Yu carefully went through the test data similar to the medical report, and then scanned the brain images, and found that it was the same as the test results in Jinshui Hospital. According to the results, Xia Yihan was in good physical and mental health. normal people.
If you spend time looking at it slowly, it will take too much time, Chu Yu will directly let Datuo dump the dry goods: "If you have any findings or doubts, tell me, to be honest, I can resist!"
For Xia Yihan's condition, Chu Yu is mainly responsible for the psychological factors, and Fang Datuo, this time mainly from neurobiology, to find out the cause of Xia Yihan, including the genetic basis, neurotransmitters, hormone system, autonomic nervous system and The study of brain functional structure.
He took the brain map, flipped through a few, and put it in front of Chu Yu, "Let's start with the functional structure of the brain, her PFC (prefrontal cortex), OFC (orbitofrontal cortex), VMPEC (ventral medial prefrontal cortex) ), DLPFC (dorsolateral prefrontal lobe), and ACC (anterior cingulate gyrus) all developed normally, with no deficits in cortical thickness."
The prefrontal cortex is closely related to self-control, impulsivity, and executive function, and affects emotional responses and moral decision-making, as well as the processing and evaluation of emotional stimuli in life. If the structure of the prefrontal cortex is abnormal, people will be impulsive and have executive dysfunction. , a lack of conscientiousness, and a sense of remorse—all hallmarks of people with antisocial personality disorder.
Chu Yu stared at the image, and the normal brain map had been engraved into her brain. By comparing the two, she knew that everything was normal, the structure was normal, and the development was healthy.
However, she is not surprised that Xiao Huaihua is obviously different from ordinary patients. For example, she is not impulsive, thoughtful, and does things without leakage. She can recognize emotions and imitate them, indicating that at least her cerebral cortex is well developed and there is no obvious dysfunction.
Pointing to the location of the amygdala in the picture, Fang Datuo continued: "Generally speaking, ASPD (antisocial personality disorder) amygdala is smaller in size and has local abnormalities, such as deformation of the basal, basolateral and central nuclei of the amygdala. , but Xiao Huaihua does not have this problem, her amygdala is perfect from volume to structure."
Looking at the diffusion tensor imaging, Chu Yu nodded: "The right uncinate tract (the white matter tract connecting the prefrontal cortex and the amygdala) is also normal."
The amygdala, which is closely involved in emotional processing and involved in moral decision-making, suffers from a lack of empathy and remorse if it goes wrong. At the same time, the connection between the amygdala and other brain regions is also particularly important. The amygdala can generally be divided into the basolateral amygdala and the central medial amygdala.
The outside of the base is responsible for receiving information, which is related to the perception and memory of emotional information.
The central medial amygdala is the output nucleus, which transmits physiological and behavioral signals related to emotion to the brainstem, cerebellum, and hypothalamus.
If the prefrontal cortex over-controls the lateral amygdala, the patient will be unable to pay attention to, perceive and learn emotional information. If the cortex does not control the central medial amygdala, the amygdala will be overactive and send signals to the brainstem, hypothalamus, etc. The autonomic nervous system outputs more negative emotions, and patients tend to be impulsive and attack others.
In response to these two items, Fang Datuo explained: "The control of the amygdala by the PEC (prefrontal cortex) cannot be concluded yet, and the results of the later experiments must be combined."
Chu Yu nodded: "Are you going to give Xiao Huaihua a certain amount of stimulation to check her brain activity under special circumstances?"
Fang Datuo nodded, "Yes, this point is also very important for the striatum. Although the picture shows that the size of the striatum of Xiao Huaihua is no different from that of ordinary people, it also depends on the size of her left side when faced with reward stimuli. degree of activation of the striatum."
Chu Yu nodded, agreeing with his method.
The striatum, especially the nucleus accumbens in the ventral striatum, affects people's reward preferences. For example, under the influence of money stimuli and sex drugs, the dopamine release of the nucleus accumbens increases, which makes antisocial personality Disabled people get more stimulation and pleasure.
After turning over the axial slice, Chu Yu held his chin, "Tell me about the hippocampus."
"In terms of volume and structure, the hippocampus is also normal. I also compared the hippocampus of Xiaohuahua with mine, and hers is healthier than mine."
Chu Yu laughed, "This is not normal. You are a super-intelligence researcher. If her hippocampus develops better than yours, isn't she super-performing and trying crazy on the edge of crime?"
Fang Datuo was a little embarrassed for such a high-profile praise. On weekdays, he was always proud of his hippocampus, and he even drew it, hung it on the wall, and specially marked it to show off.
However, Chu Yu could understand it. When Muyu and Song Qingyang passed by, they questioned their souls: "Is this a sausage drawn by Datuo? What kind of sausage can it bend like this, and its toughness is so good!"
Fang Datuo angrily tore off his hippocampus body jade photo, and has a kind of sadness that he wears luxury goods worth over 10,000 for a long time, but is considered too poor to change clothes.
Chu Yu understands his sadness, because the hippocampus is the spokesman of learning ability.
As an important part of the limbic system of the brain, the hippocampus has the function of memory and learning. If the hippocampus is asymmetrical, psychopathic behavior may occur. Psychopathy is an extreme antisocial personality disorder with obvious aggressive tendencies.
In addition, the hippocampus is also an important memory functional area. In the human brain, the parts related to memory are the temporal lobe, hippocampus and diencephalon. The temporal lobe belongs to the neocortex of the brain, and the memory of the temporal lobe is located in the superficial layer of the memory hierarchy, making it easier to forget.
The hippocampus belongs to the old cortex of the brain, and its memory is located in the deep layer of the memory hierarchy, and the memory is relatively firm; the diencephalon belongs to the brain stem, and the diencephalic memory is a deeper memory.
The hippocampus is the central part of memory.
When the brain is very interested in a certain type of information, or the information is repeated, the brain thinks that the information is extraordinary, and it not only stores it in the temporal lobe, but also transmits it to the hippocampus through the nervous system.
It is difficult to manipulate or change the deep memory circuits in the hippocampus through willpower.
The memory content in the hippocampus affects people unconsciously. If people can remember things from the age of five or six, it is because they have entered the deep memory of the hippocampus.
Chu Yu remembered Xia Yihan's dream, which was probably a real situation. It stimulated Xia Yihan too much, so he dreamed it repeatedly, but because of the repeated dream, the memory was deeper, and it was stored in the deep hippocampus. form, while influencing her behavior.
She is now carving locust flowers everywhere, because of that dream. This dream reflects on the psychological and spiritual level, which is the knot of Xia Yihan's heart, and reflects on the real criminal investigation level, which is the crux of solving the unsolved case. A dream connects the two psychological and reality. The ends are linked and interlocked, as long as one end is opened, the other end can also be solved.
But after working hard for so long, Chu Yu still felt ignorant. He moved forward in the thick fog and touched his hands forward, trying to find the iconic landmark, but found that he had only reached the periphery of the mystery and had not officially stepped into it.
After talking about the structure of the brain, Fang Datuo turned to the signal transduction substances, "Next is the level of neurotransmitters and hormones, through PET (positron emission tomography) and fMRI (functional magnetic resonance imaging), we can see Xiaohuaihua Her dopamine system is normal, and I found that the concentration of serotonin in the orbitofrontal cortex on both sides of her is the same as that of a normal person. However, based on later experiments, the amount of dopamine secretion is used as an indicator to see when she is faced with stimulation, Dopamine system activity levels."
Dopamine and serotonin are neurotransmitters, the former plays an important role in the reward process of the brain, and the release of dopamine can make people happy. On the other hand, aggressive behavior can also give people pleasure. When the dopamine system is overactive or underactive, aggressive behavior can be triggered.
Serotonin is related to emotional and behavioral control. Xia Yihan's serotonin concentration is normal, indicating that she can better control her emotions and behaviors than the general antisocial personality disorder.
But this didn't make Chu Yu happy, because the normal serotonin level only showed that it was not easy for people to launch impulsive attacks, and it had no obvious significance for premeditated attacks. And Xia Yihan's "Great Cause of Sophora japonica" is a model of premeditated crime!
Chu Yu listened to Fang Datuo, looked at various indicators, quickly scanned, and reached the hormone column, "Testosterone and cortisol concentrations are normal, but there is no daily change rhythm, and cortisol concentration changes in stressful situations. [1]"
"Yes, this requires tracking the little locust flower throughout the day to detect the levels of its various substances."
Chu Yu put the data sheet in his hand and asked, "So, is there anything unusual about this inspection?"
Fang Datuo shrugged: "No, the brain function structure, neurotransmitter, hormone levels in front of me, I also checked her autonomic nervous system, and the resting heart rate is not lower than ordinary people. [2]"
Although he expected this result, after hearing it with his own ears, Chu Yu still felt that the five flavors were mixed, and the test results were not abnormal. This is a good thing, indicating that Xia Yihan has various normal functions and there is no organic problem, but On the other hand, if the cause cannot be found, the remedy cannot be prescribed, and targeted biological assistance cannot be carried out.
Although Chu Yu's current psychological intervention methods have been somewhat effective, making Xia Yihan believe in her and willing to accept treatment, it is far from enough. At least from the point of view of Xia Yihan's emotional dysfunction, it must be determined from deeper causes and factors. Mechanism to start, to assist psychotherapy.
The next content no longer needs a projector, Fang Datuo put down the infrared pen and turned to Chu Yu, "Boss, I can check and analyze these neurobiological indicators, but the early environment is very important for ASPD (Antisocial Personality Disorder). Formation is also closely related, I don't know much about Xiao Huaihua's childhood experience, can you contribute a little?"
When Chu Yu heard this, she was shocked. The information she had picked up from Xia Yihan for so many days was finally useful, "Xiao Huaihua's childhood was not good, her mother is suspected to have depression, Or schizotypal personality disorder. On the one hand, Xiao Huaihua has genetic genes and is susceptible to mental illness [3]. On the other hand, the mother’s indifference to her has also caused emotional deprivation, which has a negative impact on emotional attachment. Insecure, emotionally damaged, and indifferent to external stimuli.”
Fang Datuo nodded: "Does her mother have the habit of smoking and drinking?"
Chu Yu shook his head, she had asked Xia Yihan about this, but was denied. Apart from being ignorant of people, Huang Nan has no bad habits, and he doesn't even scold Mu Shangqing and Xia Yihan, just treating them as air.
"Has she been abused as a child, or badly beaten?"
Chu Yu shook his head first, and then fell into deep thought: "As far as I know, no. But not necessarily, sometimes for too painful memories, especially those that happened in childhood, the human brain will choose to forget them and protect themselves. , I won't think about it, I won't hurt myself again, but sometimes, it will show in the form of a dream, such as the dream of Xiao Huaihua, I suspect, it is a serious trauma!"
Fang Datuo nodded thoughtfully, "Have you tried to unlock her dream before?"
Chu Yu glanced at him: "I've been trying all the time. The first time I came here, I forced hypnosis directly. As a result, she overreacted and almost twisted my hand off."
Fang Datuo smiled gloatingly, although he couldn't analyze the cause of Xia Yihan himself, but it didn't prevent him from laughing at the black pig, "Ahahaha, considering Xiaohuaihua's fighting power, you still dare to be tough. ...ahhahahaha!"
Chu Yu narrowed his eyes and stared at him motionless, as if a needle was about to fly out of his eye, and the needle was still stained with poison.
Fang Datuo laughed for a while, and was stabbed a few times by Chu Yu's eyes. He obeyed, the laughter stopped abruptly, and he packed up the documents on the table.
"Chu Chu, do you want Xiao Huaihua to meet us, right? It's okay, take her down. According to the current analysis results, her brain functions are normal, and she has no tendency to be impulsive and aggressive, and can be controlled well. Our own actions, and with you there, we should not be in danger."
Chu Yu nodded and said solemnly: "Well, if the follow-up experimental research shows that all her data are normal, I'm going to take surgery on her - such a large 'clue library' is in front of us, it can't be wasted!"