"The module has been loaded successfully. We are searching the news database after 2200. We found 7 similar news articles, arranged according to similarity..."
Following the sound of the system, a flashing cursor suddenly appeared in front of Nie Cai's eyes.
Those were press release titles one after another. The number of news searched this time was not at the same level as the last time. There were only a few articles.
After all, it is such a rare word, so it would be nice to have search results.
“my country has achieved a breakthrough in the treatment of tuberous sclerosis in children with the new use of the old drug rapamycin to save a critically ill girl!”
After seeing the title of the first news item, Nie Cai suddenly felt excited.
He just tried to search it just in case. Unexpectedly, this news writing assistant system was a huge treasure trove, and he directly found a crucial piece of news!
Tuberous sclerosis in children is a terminal disease now and there is no way to cure it, but in the future, this difficulty may not be able to be overcome.
As quickly as possible, Nie Cai glanced at the two to three hundred words of news. The protagonist in the news was also a twelve or thirteen year old girl who suddenly fell ill while in the hospital. The hospital accidentally mistook her symptoms for Despite the common rejection reaction, he used the wrong drug rapamycin, and his condition was immediately controlled. The situation was almost very similar to Nie Fei's.
According to the introduction in the news, rapamycin is an immunosuppressive drug that was discovered and extracted by scientists in the soil of Easter Island in Chile in 1975.
Repurposing old drugs, using existing drugs to treat new diseases, and expanding the indications of drugs are common things in the medical field, and the same is true for rapamycin.
Rapamycin is usually used to prevent rejection during organ transplantation or to treat Alzheimer's disease. However, its effectiveness in treating tuberous sclerosis was only accidentally discovered in the 22nd century, and then was reported by the news media.
Seeing this, Nie Cai finally confirmed the role of rapamycin and quickly exited the writing assistance system.
He immediately said to Vice President Ye: "Wait, don't give up the treatment!"
Nie Cai's voice was very loud, especially in the small operating room, which immediately frightened everyone.
"Mr. Nie, you have a saying in China, which is called mourning and accepting change. My sister's epileptic seizure has caused brain death. It will be the same if we continue to rescue her..."
Professor David spoke with some reluctance to comfort Nie Cai.
He thought it was because Nie Cai couldn't accept the reality that he was so excited.
"Yes, I'm sorry, but now your sister has been sentenced to death, and there is no way to save her!"
Vice President Ye sighed and took off the surgical gloves in his hands.
But Nie Cai shook his head and said excitedly: "Vice President Ye, does your hospital have rapamycin oral solution? If so, quickly bring some over and add cyclosporine and corticosteroids. This medicine can save my sister’s life!”
According to news reports, rapamycin oral solution should also be used in combination with cyclosporine and corticosteroids to achieve the best effect.
"Mr. Nie, my sister's situation is irreversible. Please express your condolences."
Seeing Nie Cai's excitement, Professor David couldn't bear to see it and advised him.
"We do have this drug, but it is used to suppress organ transplant rejection..."
Vice President Ye shook his head and didn't care about Nie Cai's proposal.
This is what happened to Nie Cai, who was suffering from an acute illness and sought medical treatment indiscriminately. You know, even the top experts in the United States were helpless. How could Nie Cai, a layman, be able to do anything
"The patient's family members please leave the treatment site. Your excitement will affect our treatment."
The head nurse was no longer so polite. Nie Cai had just barged into the operating room, which had long made her dissatisfied: "Besides, there are so many experts here who are top neurology experts at home and abroad. How can you, an ordinary person, be better than them?" Is it still powerful?"
What she said was what everyone present thought. Nie Cai was just an ordinary person. If he suddenly had to change his treatment plan, who would believe him
"Mr. Nie, I'm sorry, I can't do it according to your method..."
Vice President Ye shook his head and was about to speak, but the furious Nie Cai grabbed him by the collar and pushed him against the wall of the operating room.
"My sister had an accident in your hospital. Believe it or not, Wu Bin will never let you go!"
Nie Cai grabbed Vice Dean Ye's collar and roared ferociously.
"Okay, okay... I promise you!"
As if he was frightened by Nie Cai's appearance, or Wu Bin's name might have played a role, Vice President Ye quickly changed his words.
Feeling that the collar holding him loosened a little, he quickly said to the head nurse: "Go to the drug store quickly to prepare rapamycin oral solution, plus cyclosporine and corticosteroids!"
"Hurry up, the patient is waiting for help!"
Nie Cai's eyes were red and he urged the nurse.
The middle-aged head nurse curled her lips and left the operating room without saying anything.
Soon, the medicine Nie Cai wanted was transferred, but no one knew the dosage. In this case, they had to keep it secret. According to the dosage for treating rejection, it was injected directly into the patient through intravenous administration. Nie Fei's body.
No one is optimistic about Nie Cai. The indiscriminate treatment of this disease is simply a waste of resources.
As the pharmacist finished administering the medication, there was no movement on Nie Fei's vital sign monitor.
"Do you know how much rapamycin costs... The purely imported version costs more than 2,000 yuan for 10 ml, just for him to play with. If this person hadn't been a friend of Major Wu, he would have been kicked out of our hospital long ago!"
The head nurse murmured in a low voice, but was glared hard by Vice President Ye and did not dare to say any more.
"It must be effective... it must be effective!"
Nie Cai felt that his palms were getting sweaty and his heart was pounding...
drop-
The vital signs monitor emits a long beep, which is very harsh in the quiet ward.
"Vital signs are gone."
The anesthesiologist, who had been monitoring the vital signs monitor, finally sighed this time.
Just now, Nie Fei still had some weak signs of life, hovering on the edge of brain death. This time, Nie Fei's vital signs completely disappeared, which meant that she was truly pronounced dead.
"No, this is impossible..."
Nie Cai's heart sank, and an indescribable sadness surged into his heart.
Rapamycin is useful for tuberous sclerosis in children, but news reports are not academic papers, and key information such as dosage and administration methods cannot be reported in such detail.
It is too idealistic to think of overcoming a terminal disease that has been incurable for so long based on a piece of future news.
"I'm sorry, my brother has saved others so many times, but I can't save you..."
Nie Cai closed his eyes and stroked Nie Fei's forehead, with a sad look on his face.
I couldn't save Nie Fei, and now I'm seeking skin from a tiger, and I've offended Wu Bin. I'm afraid the days ahead will be difficult...
Suddenly, the vital signs monitor beeped twice, and the straight line representing the electrocardiogram on the screen actually fluctuated again.
"Ahem..."
Nie Fei coughed twice, opened her eyes and slowly woke up.
"What's going on...Brother, are you coming to see my surgery too?"
It seemed that the anesthesia had not worn off yet, and Nie Fei's voice was a little hoarse.
"you're awake!"
Nie Cai felt excited and quickly opened his eyes!
He knelt down and hugged Nie Fei's head, and said with great excitement: "You're actually awake... That's great, I almost thought my brother would never see you again!"
What a turn of events, Nie Fei, who was originally dead, actually "lived" again, which made Nie Cai's heavy heart suddenly go away.
Not only Nie Cai was extremely surprised, but everyone in the operating room was shocked when Nie Fei woke up again.
Nie Fei had just been sentenced to death for childhood tuberous sclerosis. Nie Cai, who knew nothing about neurology, defied all opinions and insisted on using rapamycin to treat the patient. Saved.
"Mr. Nie, this is really a miracle...my sister's epilepsy is actually showing signs of disappearing!"
Professor David clapped his hands, and soon everyone in the operating room was infected and clapped together.
Doctors are used to seeing death, but they are still excited and respectful about this miracle of life.
The blond Professor David seemed to be sighing: "I have been engaged in research in pediatric neurology for so long, and this is the first time I know that rapamycin has such a good effect in treating tuberous sclerosis in children!"
"Great, Mr. Nie, how do you know about the effect of rapamycin in treating tuberous sclerosis in children? Most people will not see this kind of drug!"
Vice President Ye also sighed and asked the questions in his heart.
His question was also the question of everyone present. If Nie Cai used penicillin to treat Nie Fei, they would be more accepting.
After all, penicillin is a drug that can be purchased in any drug store, so it is reasonable to discover its new uses by accident.
However, Nie used rapamycin!
This drug is very rare in daily life. Only those who have rejection due to organ transplantation need it, and it is not accessible to ordinary people.
"After a long illness, there are not many studies on this disease. I have been reading various papers on the Internet, and I came up with this idea by accident. If my sister had not reached the moment of life and death, I would not have dared to take it. She comes to experiment.”
Nie Cai rambled casually and gave a relatively reasonable reason.
As for whether they believed it or not, Nie Cai didn't bother to care about them.
"Mr. Nie, I suggest you publish an article in an international medical journal and then directly apply for a patent. I have calculated that there are more than 200,000 patients with tuberous sclerosis in the United States alone. It should be More, the prospects here are very broad!”
Professor David seemed to have remembered something and reminded Nie Cai.
He is an American and has a strong awareness of this kind of patent rights, so he was the first to mention it.
Today, when global medical technology research and development is relatively stagnant, this is a breakthrough, and it is a huge profit point for those big pharmaceutical companies.
Drug research and development often costs tens of millions or even billions of dollars. The discovery of new uses for old drugs can save those huge research and development expenses. As long as late-stage clinical testing is carried out, it can be submitted to the US FDA for approval.