"This is a TKI that targets EGRF, which is an epidermal growth factor receptor tyrosine kinase inhibitor. Erlotinib has performed well in bioclinical settings. Especially for those who have tried two or more chemotherapy regimens Failure of locally advanced or metastatic non-small cell lung cancer can significantly prolong the survival of advanced patients."
Li Zheng talked eloquently in the interview room. The interviewer was the famous Hector, who had interviewed successive American presidents, major political figures and wealthy businessmen in the world. The special report of "Deng and the Cowboy Hat".
This report was highly rated in China, and was even included in the textbooks for high school students in China, becoming an indelible stroke in the history of China.
"Advanced non-small cell lung cancer?" Hector had obviously done his homework, and he couldn't hide the shock on his face, "You know, there is no drug for advanced non-small cell lung cancer on the market now. In other words In other words, if non-small cell lung cancer is at an advanced stage, there is no cure. Why does erlotinib do this?”
"The development of erlotinib is a brand-new idea for anti-cancer drugs. All the secrets of the human body lie in genes, including diseases. Targeted drugs are treatments that target specific carcinogenic sites at the cellular and molecular level. ... This site can be a protein molecule inside the tumor cell, or it can be a gene segment."
Li Zheng took out a gene fragment model and pointed to the downstream of the gene fragment with his finger.
"Assuming that this is the carcinogenic site of non-small cell lung cancer, after erlotinib enters the human body, it will exclusively select the carcinogenic site to bind and act to cause specific death of tumor cells, and better than chemotherapy, it will not It affects the normal tissue cells around the tumor. Therefore, the side effects on the human body are minimized."
"Wow." Hector exclaimed, even if he was a layman, he could hear the explosive message in Li Zheng's words. It only binds to the cancer site and causes the tumor cells to die specifically. If all cancers All can operate in this way, does this mean that human beings will defeat cancer
Thinking of this, Hector couldn't help but get excited. With the advancement of technology, diseases have been conquered one by one, and cancer is the most threatening disease to human life today, and it is also the most difficult disease to overcome. If the news broke that humans have conquered cancer in his live broadcast room...
Rao is because he has experienced countless big scenes, and he can't help but have a feeling of excitement.
"Professor Li, does this mean that mankind has found a way to defeat cancer?" Hector asked impatiently.
"No, to be precise, I saw the way to defeat cancer. The biggest difficulty in the development of targeted drugs is not the molecular formula of the drug, but finding the target. There are countless genes in the human body, such as 3 billion nucleotide sequences. Looking for a single segment in so many genes is like looking for a needle in a haystack. And the Human Genome Project is doing the job."
"The establishment of a genetic map, the establishment of a physical map, the determination of DNA sequences, and the identification of genes. The completion of this plan will play a crucial role in the fight against cancer in humans. Moreover, the establishment of a genetic map is also important for the screening of treatments for genetic diseases. It means a lot."
"It seems that Professor Li is here to advertise on my program."
"Hahaha. That's right." The two laughed lightly.
"Where is Professor Li? Professor Ruiz is doing room rounds these days."
"The patient's mood is still very low. The departure of the two patients has a great impact on other patients. Even they privately rumored that our drug is not beneficial to the tumor at all. I heard that the office has received several withdrawals from the experiment. application.”
The researchers discussed softly, and after looking at yesterday's blood test data, they made routine rounds of the ward.
The "great achievements" of Ruiz and Li Zheng were played on a loop in the ward. The patients didn't seem to care, but out of the corner of the eye, they glanced at the TV unconsciously.
No one wants to die, they just lack a little hope of living.
Suddenly, two medical staff walked in from the door. They took out the videotape from the VCR, and snowflakes appeared on the TV.
Lying on the hospital bed, the patient closed his eyes and opened his eyes suddenly.
Staring closely at the movements of the medical staff, seeing the TV jump to the normal channel interface, he couldn't help but say, "Why don't you let it go?"
Yeah, why not let it go, maybe two more and they can convince themselves that maybe these two great biologists can really come up with a drug that saves their lives.
Perhaps, they really have another year, two or even five years to live.
The paramedics smiled at him and used the remote to tune the TV channel to New York.
Li Zheng's face suddenly appeared on the TV.
"Erlotinib has a good clinical performance. Especially for locally advanced or metastatic non-small cell lung cancer who have tried two or more chemotherapy regimens, it can significantly prolong the survival of advanced patients." Li Zheng The voice of the TV is clearly transmitted to the ears of everyone through the built-in audio of the TV.
The patient on the hospital bed moved with difficulty and sat up from the bed, staring without blinking at the familiar face of the young professor on the TV.
He dared to say it on the New York stage. Does this mean that this drug called erlotinib is really useful
For a time, the same idea appeared in the minds of patients in clinical trials.
Seeing Li Zheng who was late, Ruiz suddenly stood up.
He quickly walked up to Li Zheng, "Are you crazy?! It's only been a few days since the drug clinical trial started. Even if the biological experiment results are good, how can you say such things in public? If the FDA does not approve, then your reputation will be greatly damaged!"
Ruiz really appreciates this junior with a high academic level. He hopes that he can keep going. He has a hunch that this talented young man will bring them miracles. He didn't want a genius to die on the road of growth because of some trivial matter.
Li Zheng touched his nose. He felt that he might have been influenced by this young shell. At that time, when he was in Doman, his rationality had not been fully realized, and his mouth had already spoken.
This time, it was thoughtful. However, what he does does seem impulsive to others.
"This is the quickest way. The New York TV station and Hector, the representatives of authority in the hearts of Americans, only in this way can they get rid of the shadow of death and rekindle hope in the shortest possible time. As you said, the patient The mood has a great influence on our experiment." Li Zheng said.
Ruiz opened his mouth and was speechless, young man, how dare you do it!
"Li, you're amazing, really." He paused and continued, "Let's work together to make your predictions on TV come true!"
Here, Li Zheng's TV interview successfully rekindled hope in human clinical patients. On the other side of the ocean, Chinese biologists also saw the live TV video.
The Huaguo biological circle, which had been arguing for half a month, finally calmed down a little.
At least, they clearly understood the influence of this junior in their eyes, the young Huaqing professor, in the United States.
New York TV and Hector, in China, there are only a handful of people who have this treatment, and the most famous is the old man who is the most respected in China.
"This is your Professor Li from Huaqing?" an old biology senior who settled in the south asked in an uncertain tone.
As a biologist, he certainly understands the meaning of targeted drugs that Li Zheng said on TV. This is a brand-new anti-cancer drug. If it proves to be effective, based on this academic achievement, even a Nobel Prize will not be awarded to him. for too.
Moreover, this may really accelerate the development of the Human Genome Project.
"Yes." Chen Anbang nodded blankly. He had always had a very complicated emotion towards Li Zheng. Li Zheng respected him very much, and that kind of respect even surpassed Zhao Depei, and even the former Meng Jiayin. Chen Anbang didn't know why, but it didn't affect his secret joy.
However, he found that it seemed that this young back would bring him great surprises every time he appeared, and there was a growing gap between himself and him.
"Are you sure he promised you to give Hua Guo a place in the Human Genome Project?" Tian Lao asked with a cane.
"That's what he told Principal Zhao." Chen Anbang replied blankly.
Tian Lao took a deep breath and used his cane to smash the ground, "Let Xiao Zhao come over immediately and make another call in front of us!" Tian Lao's voice was loud.
"Yeah yeah."
"Don't worry if you hear it with your own ears."
"good."
Tian Lao's words caused a chorus of sympathy.
Chen Anbang nodded and was about to go out when someone suddenly said, "It's too slow to wait for him to run out to find the phone booth. Let's go directly to Xiao Zhao, doesn't he have a phone there?"
As soon as these words came out, everyone nodded.
So Zhao Depei, who was yelling at his subordinates for not doing things on the phone, looked up and saw a crowd of people standing at the door.
The phone in his hand slipped and almost fell to the ground.
"Principal? Principal?" Seeing Zhao Depei scolding halfway through the phone, he stopped abruptly. After waiting for a long time, there was no sound, and he couldn't help but cautiously said.
The "pat" call was hung up. Zhao Depei hurriedly stood up and went out.
"Tian Lao, Yang Lao, why are you here?"