After the most difficult time passed, things became smoother and smoother.
After three courses of treatment, there are enough data to prove the clinical effect of erlotinib, but at the same time, its side effects have also emerged.
"Comprehensive data show that erlotinib is suitable for third-line treatment of locally advanced or metastatic non-small cell lung cancer for which two or more chemotherapy regimens have failed." Li Zheng made the final summary.
"Yeah, it's a pity, we don't have enough time, otherwise we should have done more for EGRF's TKI." Ruiz couldn't help but sigh.
"Of course, the introduction of erlotinib is only our first step, and the discovery of EFRF represents countless possibilities. However, this data is enough for us to convince the diehards to accelerate the Human Genome Project."
Although the clinical performance of erlotinib is not amazing, it does make up for the lack of the drug market for advanced patients who have failed chemotherapy. For many people who have clinically declared that they have no therapeutic significance, it is the only A lifesaver.
So its market significance is significant.
The family members and medical staff of the state hospital almost cried with joy when they watched the patients who had been lying in bed for a long time and could not get off the ground, finally able to walk on their feet under the medication.
That sense of accomplishment made Li Zheng, who was working continuously, feel that his fatigue was swept away.
"Li, this is the charm of clinical practice. Sometimes it makes you reluctant to step into the laboratory, and sometimes it makes you feel that everything you do is valuable and sacred." Ruiz stood in Li Zheng said beside him.
Li Zheng smiled bitterly, "Fortunately, the result is good, otherwise, I'm afraid I would really choose to escape." The executioner and the savior, their work hovers between the two, for the victory of mankind, there must be sacrifice, this kind of Righteous and awe-inspiring words, he has studied countless times in textbooks, but when it comes to his mouth, he can't say anything.
The collective and the individual are always full of contradictions and paradoxes. No one can ask the individual to make concessions for the collective, no one.
Ruiz patted Li Zheng on the shoulder. All experimenters on this road must face it head-on. He used to be, and Li Zheng is now.
"I think it's time for us to go to Cold Spring Harbor. Watson and the others should have their afternoon tea ready for us."
As Ruiz once said, now Cold Spring Harbor has become a frequent place for them.
The red lecture hall, which was once regarded as a sacred place by many international colleagues, sometimes became a place for their arguments and even quarrels.
When Li Zheng and the others arrived, Watson and the others were already waiting in the office.
Watson saw the two and stood up suddenly from his seat, "It's done?"
"It's done!" Li Zheng and Ruiz nodded at the same time.
Watson and Berg looked at each other with ecstasy in their eyes. They had been entangled with those diehards for more than half a year in order to advance the Human Genome Project. Now the introduction of Erlotinib is an opportunity, and they have been waiting for the opportunity for half a year.
Li Zheng handed two thick stacks of drug data and clinical data to Watson and Berg.
Watson and Berg are also welcome. When their prestige has reached their level, they don't care about avoiding suspicion.
The two quickly flipped through the information, and the expressions on their faces became more and more intense. Although erlotinib is not a perfect drug, it is indeed the first targeted drug. It not only fills the gap for advanced non-small cell lung cancer after chemotherapy fails. The blank of drugs has opened up a new way for mankind to fight cancer.
"What about the patent, is it registered?" Watson looked up and asked.
"The patent application has been submitted." Ruiz said.
"Okay!" Watson nodded, "I believe our genome project can really start soon!"
Next is a long time for wrangling. The American scientific community is suddenly lively, one after another related reports, and members of Congress are blushing and arguing with thick necks.
Under the influence of Watson and others, the FDA accelerated the approval of erlotinib.
And Li Zheng also believed that he had done everything he could, and after saying goodbye to Watson, Ruiz and others, he set foot on the road back to China.
Of course, before returning to China, he had already agreed with Watson about participating in the Human Genome Project. As a participant in the Human Genome Project expert meeting and a person who has made great contributions to the promotion of the project, no one can question Li Zheng's right to participate in this project. Li Zheng and Li Zheng's team are important members of the human genome project research group , this is already an established fact.
"This plan requires extensive participation from all countries in the world. China is a country with a population that accounts for one-fifth of the world's population. From a scientific perspective, we welcome the participation of China. But Li, you know, politics is always a thing. It's very ugly, and I can only promise you to try your best." These are Watson's exact words.
Li Zheng didn't say hello in advance when he returned to China this time. When he saw that there were only two Huaqing students in the lab, he couldn't help raising his eyebrows. Those little brats dared to be lazy while he was away.
"Li... Professor Li." A Huaqing student said tentatively.
Li Zheng threw the bag in his hand on the sofa, "Where are Meng Jie, Sun Bin and the others?"
"Mr. Meng and Mr. Sun have gone to the Academy of Sciences." The Huaqing student thought about it and added, "Academician Tian asked them to go."
Li Zheng smiled, Meng Jie, Sun Bin and the others were actually called teachers. As for the fact that they were called by Tian Lao to go to the Academy, Li Zheng could also guess.
On that day, after Hetian Lao and the others said that he could only ensure that his team members would participate in the Human Genome Project, Tian Lao and others were silent for a while. Li Zheng understood their feelings. I feel happy in this project, but on the one hand I feel resentful that I and others can't participate, but a few little kids can.
But in the end, they put the glory of the country ahead of themselves, which is why Meng Jie and others went to the Academy of Sciences.
Li Zheng nodded, "I'm going back to the jet lag, they're back, go to the room and call me." He ordered and walked back.
By the time Meng Jie and the others came back, it was almost seven o'clock in the evening. Besides the three of them, there were also Zhao Depei, Tian Lao and Yang Lao.
This is the first time for Tian Lao and Yang Lao to enter the ninth laboratory. "This equipment is much better than that of our Academy of Sciences. No wonder the experimental methods of these two boys are so rough. With such equipment, the requirements for methods are much lower."
Meng Jie and the three kept their heads down and didn't speak, like defeated roosters. They had been practiced by Mr. Tian and Mr. Yang in the past few days, and they finally knew how generous Professor Li was to them.
The two Huaqing students were also smart. When they saw a few people coming in, they rushed to the villa behind to see Li Zheng, so when Li Zheng came over, he happened to meet a few people.
"Professor Li!" Sun Bin's eyes were sharpest. When he saw Li Zheng, it was as if he had seen some kind of savior, and he ran over quickly. Li Zheng avoided Sun Bin's open arm.
"After all, don't be so excited." Li Zheng showed a helpless look on his face, "Principal, two seniors, sit down."
He pointed to the sofa beside him and said.
It was the first time for Mr. Tian and Mr. Yang to see Li Zheng, and they had heard Professor Li's very young words countless times, but when they actually saw this young man in a denim T-shirt, they were still a little sighed.
"The back waves of the Yangtze River push the front waves. Professor Li is really a heroic boy." Tian Xiangjun couldn't help but smile bitterly.
Li Zheng waved his hand, "Tian Lao, you are very kind, Tian Lao is the role model of my generation, the founder of Huaguo biology."
Tian Xiangjun shook his head, "Let's stop praising each other, let's get to the point. I heard that at the beginning of the year, the U.S. Department of Energy and the National Academy of Medicine allocated $5.5 million to build a laboratory. The news of the Human Genome Project is buzzing, you give me a word, will the project start within this year?"
Tian Xiangjun also made some efforts after talking with Li Zheng last time. Although China's economy developed steadily in 1987, there are too many places to spend money in such a big country. More willing to invest in visible military industry.
Tian Xiangjun used almost all his contacts to explain the importance of the Human Genome Project to the leaders over and over again. Finally, at the end of last month, someone in the central government let go.
However, this year's national scientific research budget has been allocated, and Hua Guo will put the scientific research work of the Human Genome Project on the agenda in the next few years.
"Yes!" Li Zheng said without any hesitation.
Before he left the United States, biologists headed by Watson had basically persuaded the U.S. Congress that as long as the laboratory was completed, the Human Genome Project would be officially announced.
"I see." Tian Lao looked a little depressed.
In this life, because of Li Zheng's intervention and the early launch of anti-cancer targeted drugs, the people of the world have truly felt the great power hidden in genes.
Compared with the Human Genome Project carried out by various countries in the previous life, the Human Genome Project this time presents a situation of blooming everywhere.
Italy, the United Kingdom, the United States, Germany, and France have launched projects one after another, and there is a tendency to unite, which makes Chinese scientists who have been excluded from the system even more anxious.
When the United States announced the official launch of HGP, and the integration of resources from various countries joined in, this was the most difficult time for the biological circle in China.
It's just that Li Zheng was helpless.
Project cooperation must be exchanged on an equal footing. At present, China does not have a foundation for human genetic research, nor does it have strong financial sponsorship. Governments of various countries will not allow China to participate in this project.
What Li Zheng can do now is to let Chinese scientists headed by him participate in the project, and make an opening in this project team composed of major countries in the world, so that when Huaguo has the ability to participate in the future, it will not be the same as in the previous life. That's tough.