The proposal of Zhen Zhe management as the first batch of clinical volunteers for HPV vaccine was put forward by Zheng Lingling. Li Zheng, Liu Sichao, Zhang Chao and other project workers couldn't wait to try the vaccine effect on themselves as early as the end of the biological trial.
Zheng Lingling saw a group of big men injecting herself with the HPV vaccine, with an undisguised look of disgust, she proposed that she would also be willing to receive the vaccine, but Li Zheng stopped her.
Li Zheng had prepared for the worst. In case the drug clinic really couldn't recruit volunteers, they would have to do it by themselves. Let's keep this precious woman, Zheng Lingling.
Just before Li Zheng came to make his last attempt, Zheng Lingling told him that Zhenzhe's management was unanimously willing to be the first batch of volunteers for the HPV vaccine.
Li Zheng's statement that he was not moved must be a lie. Except for the three or four people from the original Li Zheng's laboratory, the management of Zhenzhen are all new colleagues. The new colleagues can make such a decision. This is for Li Zhengji. Great trust.
Li Zheng's words were loud, especially the last sentence, which made the entire conference room riot again.
In foreign countries, it is not uncommon for researchers to test drugs by themselves. For example, the clinical road of the hepatitis B vaccine has been twists and turns. When it was first submitted to the FDA, the FDA rejected its application.
The vaccine project staff injected themselves, followed by the people around them, and it slowly spread. It took a few years for the FDA to officially approve the clinical application for this project.
In China, this seems to be a remarkable thing. The eyes of the seniors looking at Li Zheng changed instantly. They knew that Professor Li had extraordinary achievements in pharmacy, but they didn't expect that in addition to his academic level, this person's ideological and moral level was even more amazing.
In order to develop a vaccine to prevent cervical cancer, exposing yourself to the HPV virus is doing research at the risk of your life!
Everyone felt that the documents at hand became a little heavy.
The fans of the Yanjing Hotel were still rattling. A group of biology scholars took out the pens in their breast pockets and began to write and draw on the materials. They began to seriously evaluate the clinical feasibility of this project.
Li Zheng's dignified expression slowed down a little, and he was willing to take a serious look.
Time passed by, and apart from the sound of the fan, the only sound in the conference room could be the sound of pages turning over.
"What are the old men doing in there? We are going to get off work." Outside the conference room, several aunts in their forties gathered together.
The state-run guest house is not like the hotels of later generations who provide round-the-clock smiling service. Now that the get off work time is up, a group of old men are still stuck in the conference room, which makes these aunties unhappy. They also want to go home early to rest.
"How about we go in to remind you?"
"Go, go, if it weren't for the old people inside, I would want to go in and shoot them away!" Someone said.
So these bigwigs, who are among the best in China's biological circles, encountered the most embarrassing thing in their life.
A few middle-aged aunts dressed as service staff of Yanjing Hotel walked into the conference room with their waists on their arms, and said in Beijing dialect with a strong accent: "It's time for get off work, it's time for get off work, we're going to get off work, you can go to another place. read a book."
Everyone was stunned at first, and then they didn't know who started, and there was a huge burst of laughter.
Yang Lao held back his laughter and stood up with a dry cough, "Okay, big girl, we'll change places." He said hello to everyone to get up.
The big guys all had smiles on their faces, and while taking things neatly, they smiled and apologized to several service staff, "I'm sorry, big sister, for delaying you from get off work."
By the time the leaders of the Yanjing Hotel hurried over, half of the bosses had already stepped out of the gate of the Yanjing Hotel.
This time the conference room was reserved by Yang Lao, and the cold sweat on the leader's forehead kept coming out. He just forgot to say one more thing, how could this happen.
You must know that although these people are not high-ranking officials with real power, several levels are above the main hall, and these experts and scholars may all be able to reach the sky.
"Old Yang, this..."
"It's okay, we're wasting your time, don't worry."
"But… "
"No need." Old Yang patted the leader's shoulder, then walked out the door with a smile.
Everyone didn't take it to heart at all, and some people even thought it was funny, and there was another joke to talk about after dinner.
After the meeting, the drug administration department debated for three months on whether to approve the clinical application of the HPV vaccine. On August 1, 1990, the first vaccine-based original drug of Huaguo was launched for the first time in Huajing. Drug clinical.
Professor Li Zheng, the first among the middle-aged biologists in China, injected the HPV vaccine into his body under the live broadcast of CTV, demonstrating the safety of the vaccine with facts.
"The first batch of 50 clinical practitioners, 17 have signed up so far, 8 are people who are too poor to live on, counting on the trial fees. The other 9..." Zhang Chao paused, his face showing strange With a smile, "The other 9 are students from the biology departments of various universities in Huajing. They admire you very much. Some people even proposed that they only need to meet you without the test fee."
Li Zheng was stunned for a moment, then smiled, is he enjoying the treatment of an idol
But Li Zheng didn't understand what the real idol effect was until a few days later.
Li Zheng originally planned to officially start the first clinical trial of the drug on August 15, that is, half a month after the approval order, but as the time was getting closer, the first batch of 50 places had not been filled.
Zhang Chao was anxious, and when he contacted Xiang Jiang, he couldn't help but confided a few words, which spread to Zhou Sitian's ears.
Without saying a word, Zhou Sitian came to the inland without Li Zheng, and publicly announced as a Hong Kong star to become a clinical volunteer of the HPV vaccine.
This time, both Xiangjiang and the inland shook.
It is said that the influence of those little fresh meat in later generations is great, but in terms of influence, the influence of those Hong Kong jade female stars in the 1980s and 1990s was definitely not worse than the little fresh meat of later generations, or even higher than them.
Zhou Sitian's public registration has attracted many people from Xiangjiang to join the HPV vaccine clinical trial in Huajing, and the mainland is also there. It didn't take long for the news to spread, and the 50 places were full, and some people even stayed at the hospital entrance. Must participate. The staff repeatedly persuaded, but refused to leave.
"Sister, your influence is really great." Li Zheng couldn't help sighing when he saw the number of places filled two hours after the news spread.
"I have read the data that cervical cancer is the second most common tumor in women after breast cancer. If I can do my part to eliminate cervical cancer, it will be good for me both in public and private." Zhou Sitian smiled. said.
A hint of softness flashed in Li Zheng's eyes, this is his sister, that's what he is. He refuses to admit that he made this decision because he loves his younger brother, and uses his own life to seek a false name. Zhou Sitian has never been this way. kind of people.
"Sister, thank you." Li Zheng said softly.
Zhou Sitian glanced at him, "It's better to take care of yourself than to say thank you, there is no day or night all day, I didn't like Liang Zhe at first, but now I think it's him, otherwise who can stand you !"
Li Zheng…
Due to Zhou Sitian's influence, the first batch of 50 volunteers started the clinical trial of the drug smoothly, and the clinical trial went very smoothly. After the 50 volunteers were injected with the HPV vaccine, 100% of the subjects developed anti-HPV virus. antibodies, and reduced the risk of infection by 94% under a single exposure and HPV virus, and 86% of people were still protected and uninfected under six exposures and HPV.
As soon as the result came out, everyone was very excited. A group of biologists, including Yang Lao, were also very concerned about this clinical trial. After all, if it is successful, this HPV vaccine can be called the first vaccine to a certain extent. cancer vaccine.
With the full cooperation of the drug administration department, on October 25, 1990, the second drug clinical trial was launched in Huajing First Hospital.
This time, the scale has been expanded, and the number of participants in the experiment has reached 200, which is the largest in the history of Chinese drug clinical trials.
The more people there are, the more things will happen. The old man's words are not false at all. This time, Li Zheng's luck is obviously not so good. On November 6, 1990, the first death case in the history of Huaguo's drug clinical trials was born in Huajing First Hospital.
"I'm not breathing, the 17-bed volunteers are not breathing!" The nurse on the night watch exclaimed and ran out, "Go and inform the director, contact Dr. Hu and the laboratory! Go!"
The deceased was a female university student named Zhang Xiaoke. Her boyfriend is from the Department of Biology in Huaqing, and he admires Li Zheng very much. He mutters every day that if he is a woman, he must participate in the HPV vaccine clinical trial. Zhang Xiaoke signed up for this clinical trial as soon as he heard it.
When Li Zheng received the notice, it was after one o'clock in the morning, and he and Zhang Chao rushed over as quickly as possible.
"It has already been rescued, but the rescue is ineffective, and the death was at 0:26." Dr. Hu said solemnly.
The faces of the officials of the drug control department were so black that water dripped from their faces, and the worst had happened. "What about the cause of death, is it because of the vaccine?" he asked.
Dr. Hu shook his head, "It's impossible to tell the cause of death alone."
"Then what to do, you are doctors, you can think of a way!"
"It needs to be dissected, isn't it?" Li Zheng, who had been silent, looked up at Dr. Hu.
Hu Zhongming sighed, "Yes, we need to dissect it. We need to obtain the consent of the family."
Everyone in the room was silent for a while. They could say what they said. A good person came to participate in the drug clinical trial and an accident happened. This person is dead, and they have to dissect other people's corpses. These words must be smashed by someone.
"Professor Li, you can rest assured that since our drug administration department has approved this drug clinical trial, we will take care of this matter. I have seen the effect of the drug with my own eyes. This matter will delay the time to market for the drug at most." The official of the department is the one who dares to take responsibility, and that's what he said.