"Li... Li Zheng, do you know..." Zhang Yuejun ran in from outside panting.
Li Zheng and Xu Mingsheng had already changed into their lab coats. Li Zheng compared the indicators of a group of mice and raised his eyelids slightly when he saw Zhang Yuejun come in.
"Come on, change your clothes."
Zhang Yuejun opened his mouth, he hurriedly put on his shoe covers, put on a white coat, then put the mask on his face, and trotted to Li Zheng's side.
"Patent...India..." Li Zheng frowned slightly before he could breathe, "You can't breathe through your mouth in the lab, I thought it was common sense."
Zhang Yuejun's face became solemn, and he subconsciously closed his mouth and held his breath. Seeing his face became more and more red, Li Zheng reluctantly took off his mask, "It's okay to breathe through the nose."
Zhang Yuejun patted his head, "Oh, my eyebrows are on fire, you still have to control this, do you know..."
"I know." Li Zheng stuffed a tube of reagents into Zhang Yuejun's hands, "I have already adjusted the ratio, and I will inject these mice in fifteen minutes."
"When the data of these batches of mice comes out, the clinical data will only be worse than the actual part of the human body." Li Zheng closed the record book with a smile.
Zhang Yuejun scratched his head and wanted to say something, but Xu Mingsheng, who was on the side, finally couldn't stand it anymore, "Okay, Xiao Zhang, we already know about the generic drugs in India, Li Zheng has his own plans, you take care of the animals. The experiment is over, and the second work will not be without you."
Zhang Yuejun's mouth widened in astonishment.
Li Zheng rolled his eyes and put a mask on his face. The laboratory disinfection work in the 1980s was not as sophisticated as later generations, and the laboratory of Hong Kong University likes to study various viruses, and the young man has a big heart.
A batch of 100 mice, a total of 20 groups of experimental comparison groups.
fifteen days later
"A batch of mice was divided into two groups according to your design. One group was artificially injected with prothrombin, and the other group was healthy. One was an overdose of prothrombin, and the betadine died before it had time to work. The other..." Zhang Yuejun scratched his head, "The other one, according to the test results, died..."
Li Zheng paused as he filled in the data, and drew an unsightly black line on the record book.
"In the future, the food of the mice used in the experiment will be halved."
"There is also the group that was not injected with prothrombin. Fifty mice did not die. Among them, on the first and second days of the experiment, 16 mice had rapid heartbeat and shortness of breath. This phenomenon occurred on the third day. Relief. There is also a white mouse with alopecia areata. As for whether it is a special case, more experimental comparisons are needed. "
Li Zheng nodded, "Proportionally adjust the concentration of paminosatin, test the optimal ratio, and record all the special phenomena that occurred in the experiment. Then add mice to see if it is the cause of the drug."
Li Zheng has already started to write the paper. The last paper he read at the Asian Biological Congress was only the first draft. Around an original drug, more than a dozen papers can be written, and each of them is SCI, which is enough to see the preciousness of the original drug.
These 15 days are enough for the public opinion of Indian generic drugs to ferment in Hong Kong and mainland China. There is no original medicine in mainland China, so does Xiangjiang have it? No.
Yes, even if it is as developed as Xiangjiang, there is no original drug developed by a real Xiangjiang company. Therefore, after Li Zheng publicly announced the development of an original drug at the Asian Biopharmaceutical Conference, the people of Hong Kong also felt a sense of pride. After all, Li Zheng is a student of Hong Kong University. As for whether Li Zheng is from Hong Kong, all the media have avoided this topic invariably.
Heung Kong Daily ran a front-page headline condemning India for not respecting patent rights for several days. In mainland China, there has been a storm of public opinion.
In inland China in the 1980s, the communication of information was not as developed as in later generations. Newspapers were the main way for intellectuals at that time to understand the times. Because Li Zheng is from China, Zhu Xin has been paying attention to the research progress of paminesatine, and he has supplemented various knowledge in the pharmaceutical industry in the past few days.
I know that although Li Zheng has disclosed the molecular formula of the drug, from the birth of the molecular formula of the drug to the launch of the drug, a large amount of information needs to be provided to pass the drug approval. Heungkong is now part of the United Kingdom of Great Britain and Northern Ireland, and the listing of drugs in Heungkong needs to be approved by MHRA, the UK Medicines and Health Products Regulatory Authority.
This time can be as short as three or two months or as long as one or two years. Zhu Xin has made up his mind. When the betadine drug is officially launched, he can plan a special report, even if he directly flew to Xiangjiang to interview this little genius. .
but!
Generic drugs!
Or Indian generics!
In 1962, the Sino-Indian border friction broke out, and the Sino-Indian war broke out in June. Although more than ten years have passed, the Chinese people's perception of India has always been poor. At this time, the Indians have come to do this again, and Zhu Xin can't wait to directly smear the newspapers on their faces.
In anger, Zhu Xin personally caught the knife and wrote a report, which once again pushed the name of Li Zheng into the attention of the Chinese people, especially the Chinese intellectuals.
In the office of Huaguo Railway's secretary, Zhao Mu welcomed a special guest.
"Professor Meng? Why are you here. Xiao Wang, pour some tea." He said the last sentence to the secretary at the door.
Secretary Xiao Wang responded and trotted out with a hot water bottle.
"Little Zhao, your health is okay. You're a lot older." Meng Jiayin looked at Zhao Mu, whose hair was gray, and couldn't help but feel a little sighed in his heart. How many old guys and comrades didn't suffer the accident in 1968? past. If it hadn't been for him having taken up his post at the Chinese Academy of Sciences early, and he had another project on hand, I'm afraid he wouldn't be able to escape.
"Professor Meng, you still look so young." Meng Jiayin was seven or eight years older than Zhao Mu, but now that they were standing together, Zhao Mu looked older.
"They're all old men. They're still young. Life will pass, and now the hardships are over. You have to cheer up. Li Hua doesn't want to see you like this."
Li Hua, also known as Zhao Mu's wife, was a former student of Peking University. Because of student activities, he was very familiar with Meng Jiayin. When Li Hua and Zhao Mu got married, Meng Jiayin was still with another Yanjing University professor. hosted.
Speaking of his deceased wife, Zhao Mu's mood suddenly fell, and he forced a smile, "Meng Lao, I know, I am living well now."
Meng Jiayin looked at Zhao Mu's appearance, shook his head and said no more.
Zhao Mu was reinstated in April, and his daughter Zhao Qiuhua left the Shenzhen market at the end of March. This has to be said to be fate.
Meng Jiayin has been thinking, if Zhao Qiuhua persists for a few more days, will the high-spirited genius at the Asian Biopharmaceutical Conference be his student.
Well, even if it's not a student, it's a colleague.
"I'm not going around with you anymore, Xiao Zhao, I came to you today to talk to you about your grandson." Meng Jiayin said with a smile.
Zhao Mu was taken aback, "Xiao Zheng?" He just received a letter from his daughter two days ago.
Because it was an overseas letter, after layers of review, it was already eight months after it arrived in his hands. He called an old acquaintance in Shenzhen a few days ago and asked him to help deliver his grandson and granddaughter to the office. Huajing.
In fact, when Zhao Qiuhua left, Zhao Mu knew and supported him. In his life, he was worthy of the world, the party, and the people. The only thing he owed was his daughter.
Her daughter obviously has a bright future, but because she has suffered so much and has to take care of herself, she is trapped in the small place of Qinghe Town.
Zhao Mu was happy when his daughter made up his mind to leave. Although he also knew that he was sorry for Li Qiang and his two children, every father was selfish, and he hoped his daughter would be happy.
"Are you talking about my grandson Li Zheng?"
Hearing the words "Li Zheng" from Zhao Mu's mouth, Meng Jiayin's smile became even more obvious.
"Little Zhao, you have a good grandson. We relied on him to clear the siege last time in Tokyo. Moreover, Mr. Li Zheng's academic level is very high, higher than me!" Meng Jiayin did not hesitate to praise.
Zhao Mu was obviously taken aback by Meng Jiayin's words, "Meng Lao, you may be mistaken, my grandson is only 17 years old this year, he is still a child."
Meng Jiayin looked at Zhao Mu strangely, and took out a few newspapers from his bag.
"The first few are from Xinghua Society and People's Daily, and the latter are from foreign media. They are all about your grandson, an original drug! We study biology, and who doesn't want to develop an original drug that can save lives. The guy is very generous, the original drug for special diseases, and the molecular formula is published, although it has been copied by India because of this, how many lives can it save! India is a big country with cold blood disease!"
Meng Jiayin was a little excited when he said it. Li Zheng's actions really resonated with scholars of this era!
Zhao Mu picked up the newspaper from the table and hurriedly browsed it, a storm surged in his heart.
This Xinghua Society and foreign media spent a lot of praise on... Is it really his grandson? how can that be!
However, Li Zheng's face was clearly printed on the newspaper. Zhao Mu and his grandson had only been separated for more than half a year. Naturally, he recognized the confident young man on the stage in this photo at a glance. It was his grandson Li Zheng. !
"How is this possible! How could Xiao Zheng be in Tokyo?"
Twenty days later, all the comparative experiments came out.
The results of the experiment showed that the cure rate of paminesatine for infants and young children with cryoemia was as high as 91.27%, and the best effect was to be given once a week for three months. Paminosatin has side effects on the respiratory tract and heart. The main manifestation is that within 48 hours after injection, the phenomenon of rapid heartbeat and shortness of breath will appear, and it will automatically relieve after 48 hours without sequelae.
Alopecia areata occurs due to the rejection of the trace elements in paminesatine and the cells that promote hair growth in the living body. The occurrence rate of the phenomenon is 3 in 1,000, which is in line with the relevant regulations of HMRA.
Li Zheng closed the notebook, and he already had a stack of living clinical materials at hand.
"Teacher, lawyer Cheng has already applied for all the thirty-nine patents on pamibutin. Now I have to trouble you to contact the Indian side. I am willing to provide pamibutin injections for free as a comparison sample for their in vivo clinical experiments. ."