It was the drug eruption, and the side effects of the carbapenem antibiotics started.
"Monitoring the body temperature and electrocardiogram, can you hear my voice, teacher? Don't be afraid. If you feel vomiting, it's normal. Just bear with it, and half an hour will pass." Li Zheng looked at the mechanical watch on his wrist, He said calmly.
He has experienced numerous drug clinical trials, but this time is definitely the most special drug clinical trial.
"Wang Jing, are you ready, intramuscular injection in five minutes."
Wang Jing swallowed her saliva and nodded vigorously, her hand holding the syringe trembled slightly.
"Nausea" Xu Mingsheng's face suddenly turned blue and white, he suddenly turned to the side of the bed and retched, and vomited out the millet porridge that he finally fed in in the morning.
Chen Sufen stepped forward and patted Xu Mingsheng's back lightly, "Li Zheng's medicine made Lao Xu spit it out."
"Feed it in again!" Li Zheng said without thinking.
Xu Mingsheng's retching continued, he couldn't vomit anything, but his stomach was churning like an earthquake, and he lay weakly by the bed, almost vomiting out the gallbladder water.
"Old Xu, you must eat it!" Chen Sufen's eyes flashed with tears, she opened Xu Mingsheng's mouth, and forcefully poured the medicine into his mouth.
Xu Mingsheng looked in pain, he couldn't stop shaking his head, but Chen Sufen didn't give up, covering his mouth and wouldn't let go.
Bitter bile flowed along Xu Mingsheng's mouth and touched Chen Sufen's hand, but Chen Sufen still did not let go.
The second hand turned twelve o'clock, Li Zheng raised his head, "Wang Jing, intramuscular injection."
"Hey!" Wang Jing responded heavily. She took a deep breath and grabbed one of Xu Mingsheng's arms. Xu Mingsheng's arm was very stiff due to violent vomiting.
"Professor Xu, take it easy, otherwise it will hurt a little." Wang Jing said, pressing hard on the lower edge of Xu Mingsheng's deltoid muscle.
The medicine was pushed into Xu Mingsheng's body smoothly, Wang Jing wiped the sweat on his forehead, and then looked at Li Zheng.
Li Zheng looked away from his watch, nodded to her, and stopped talking. Next, he had to look at Xu Mingsheng himself.
He has seen Xu Mingsheng's case and medication records. Xu Mingsheng has no history of antibiotic allergy, and carbapenems do not have penicillin-like thiazole rings, and generally there is no cross-allergic reaction. Li Zheng's only concern is the nephrotoxicity of the drug.
Compared with imipenem, which was marketed in 1985 and 1985, the carbapenems extracted by Li Zheng have not done biological detoxification, and have not done the ratio and dilution of drug components, which requires the patient's own immune resistance. Strength and will to survive.
Every minute and second that followed was very difficult for the people in the ward. Xu Mingsheng's drug rash and retching reactions became more and more severe. The red rashes densely covered his arms and spread to his face.
The blue veins on Chen Sufen's forehead burst out, and everyone knew that she was holding back her grief.
After an hour or two, Xu Mingsheng's reaction gradually became calmer. He seemed to be a man who almost drowned. He finally swam to the shore and took a big mouthful of fresh air.
"It's falling! Lao Xu's body temperature is falling!" Chen Sufen looked at the numbers on the temperature monitor, her voice trembling slightly.
There was an instant commotion in the ward, Xu Keqiang was sticking his whole body to the temperature monitor, 38.7 degrees Celsius, still a high temperature, but compared to the high temperature of more than 39 degrees that lasted for several days, it was already an extremely surprising figure.
Everyone looked at Li Zheng with reverence. This seventeen-year-old boy was not tall. Is there really a genius in the world
Now they can answer without hesitation, there is one in front of them!
"Teacher, the duration of the carbapenem nephrotoxicity outbreak is only within three hours after the drug enters the human body. The teacher has passed the dangerous period. In another hour, his body temperature will drop. He's almost done with some dextrose."
Chen Sufen covered her mouth excitedly, she wiped the excited tears from her eyes, "Thank you, thank you Li Zheng!"
"Thank you, Li Zheng!" Xu Keqiang said.
"Little Junior Brother, you are really amazing!"
"Little Junior Brother, it's great!"
The dull atmosphere in the ward was swept away, everyone's originally heavy hearts became relaxed, and the atmosphere in the room suddenly became warm and cheerful.
However, Li Zheng's tense nerves still did not relax, he looked at the watch on his wrist, it was almost seven in the morning.
"Professor Chen, how are the patients in the isolation room outside?"
Li Zheng thought that with the example of Xu Mingsheng, the hospital should be more accepting of this brand-new antibiotic.
When Chen Sufen heard the words, she also slightly put away her excitement, and the expression on her face became serious.
"As of 5 a.m., two people died in the isolation ward, three people were admitted to the emergency room due to organ failure, and the rest continued to use antibiotics."
"Professor Chen, I think..." Before Li Zheng could finish speaking, Chen Sufen interrupted him.
"Mr. Li Zheng, on behalf of the Queen Mary Hospital, I implore you to sell the carbapenem antibiotics in your hands as a special drug temporarily purchased by our hospital." Chen Sufen looked serious, but looked at Li Zheng with a very gentle gaze. .
Li Zheng was stunned for a moment, then realized that Professor Chen was protecting him by doing this.
She purchases medicines on behalf of the Queen Mary Hospital. If a patient dies due to drug toxicity, the first one will be the Queen Mary Hospital. Although Li Zheng, the supplier, is also involved, there is a lot of room for maneuvering.
Chen Sufen wanted to protect Li Zheng to the greatest extent possible under the worst plan.
Li Zheng couldn't help but feel a little moved, he opened his mouth and was speechless.
"Mother..."
Chen Sufen stepped forward and patted Li Zheng on the shoulder, "Good boy, you are a treasure bestowed by God to mankind, you should stay in the laboratory and concentrate on your research. Leave the rest to us."
Chen Sufen is a professor at the Department of Clinical Medicine of Heung Kong University School of Medicine, but what few people know is that Chen Sufen also holds 3% of the shares of Queen Mary Hospital, so she can speak on behalf of the hospital, but it's just that she can't say it accurately, and she still has a problem. Have to talk to the rest of the Queen Mary Hospital.
"Aqiang, you look at your father, I'll go out." After speaking, she sorted out Xu Mingsheng's case, and then walked out with a stack of thick documents.
Li Zheng pursed his lips and followed.
"Master, there are some things in the experiment notes that only I can explain."
"No! Absolutely not! There is no drug on the market, and even the drug has not passed the clinical trial, how can we try it on our patients! This is a crime!" The vice president of Mary Hospital put the quilt heavily on the table, gasping for breath Rough.
Chen Sufen slapped the table heavily, "Chen Xuhua, who are you saying is committing a crime!"
Dean Chen's aura suddenly weakened, "Teacher, that's not what I meant."
He scratched his head vigorously. Chen Xuhua hadn't slept for two days and two nights. He is the vice president of Queen Mary Hospital and the director of surgical oncology. This Pseudomonas aeruginosa infection started in the ICU ward of surgical oncology. . When the infection first broke out, he only thought it was a mutation of the influenza virus, and only ordered to strengthen the disinfection, but did not intend to cause a hospital-wide drug-resistant infection.
Chen Xuhua felt self-blame and annoyed. He had been in the front line for the past two days, and had been to the isolation room several times. He kept telling patients to have confidence and will to survive.
When the patient looked at him with hopeful eyes and asked him, "President Chen, can we still be saved?", he nodded vigorously, and the tears flowed directly.
He's still a doctor, so many patients who are struggling to survive, he can't save any of them!
"Teacher, ensuring drug safety is the basic professional ethics of a doctor! Physician guidelines, and the relevant provisions in the doctor's practice regulations..." Chen Xuhua was brought out by Chen Sufen, and he still respects the teaching teachers.
Chen Sufen's attitude also eased, "Xiao Chen, Lao Xu has already taken medicine, here is his medication record and drug reaction report, carbapenem antibiotics are effective! Physician guidelines and professional regulations are up to me. With what you read, I can understand these terms clearly, but Xiao Chen, do you still remember the first sentence I said to you in the first class? The patient's life is above everything else!"
When Chen Xuhua heard the words, his expression was a little dazed. He seemed to have thought of something, and he didn't speak for a long time.
"I am 80% sure that I will be responsible for all the consequences after the patient is injected with antibiotics." Chen Sufen's always gentle face was full of seriousness.
Standing there with her not-so-tall body, Chen Xuhua felt as if she had returned to that humble classroom more than 20 years ago, and Professor Chen had the same expression.
He remembered that Professor Chen walked into the classroom with a book in his hand, and the first sentence was, "You will all be doctors in the future. What is the doctor's job? It is to treat and save people. I hope that no matter where you go in the future, no matter what position you are in, you will never forget the patient. Life is above all else!"
Chen Xuhua slammed the table and stood up, "I see, teacher." He took Xu Mingsheng's case from Chen Sufen's hand and studied it carefully.
Li Zheng stepped forward and explained to him the principle of action of carbapenems, drug effects and defects.
Chen Xuhua couldn't help nodding his head, looking at Li Zheng with shock and admiration, "It is said that the great man is the one who serves the country and the people. Mr. Li Zheng, you are the chivalrous man among scholars!"
Li Zheng shook his head, "President Chen, you are wrong. I'm just an experimenter. Without the courage of you and Professor Chen, these things of mine would not be of any use."
Li Zheng really admired the high-end intellectuals in the 1980s. They paid more attention to being a person while doing their studies. You can see the shining points accumulated by the Chinese nation in them. To be honest, if he wanted to do this in his era, he probably needed to write a lot of promises, promising that all the consequences of this would be borne by him personally.
Chen Xuhua smiled bitterly, "Mr. Adolf is not a problem, I'll tell you. Mr. Li Zheng please go back and prepare enough potions. What you have in this box is far from enough."
"Teacher, I called the doctors in the hospital to screen patients with normal renal function and immune resistance, and inject medicine first."
Li Zheng's expression froze when he heard the words. Chen Xuhua's meaning was very clear. Patients with renal dysfunction and poor immunity will not be given injections for the time being, which means that these people have no chance to challenge, and they have already been sentenced to death. Li Zheng shook his head with a wry smile, everything in the world is difficult, this is already the best way to get the best of both worlds, isn't it