"I'm old, I'm really old, but after two or three days of boiling, this head doesn't seem to be my own." Su Changzhi stretched and put the last tube of antibiotic extract into the incubator.
In the past few days, the professors from the School of Medicine of Xiangjiang University, headed by Su Changzhi, completely put down their work, soaked in the laboratory with Li Zheng, ate some bread when they were hungry, and leaned against the table for a while when they were sleepy. Together, 200 carbapenems were sent to Queen Mary Hospital.
"Professor Xu just called. He has completely escaped the dangerous period, and his wounds are recovering well. If there is no accident, he will be discharged from the hospital in a week." Li Zheng announced the good news to everyone with a smile.
The professors were really happy.
"Good Xu Mingsheng, when he is discharged from the hospital, we must have a good meal at his house, my old arm and old leg." An old professor said while pressing his shoulder, causing a burst of laughter in the laboratory Voice.
There was laughter and laughter in Qingyuan, but another scene in the hospital.
As of last night, the Queen Mary Hospital confirmed 87 people infected, 78 of whom were injected with carbapenem antibiotics, successfully passed the dangerous period, and have been sent back to the general ward.
But the remaining nine people are either old or suffering from other severe diseases and their resistance is extremely weak. Experts at Queen Mary Hospital have assessed that these people have less than a 20 percent chance of surviving antibiotic nephrotoxicity.
"The 18-bed and 24-bed patients have shown signs of organ failure. The situation of the remaining seven patients is not very good. The drug-resistant bacterial infection has caused various complications. I think we need a collective vote on whether to inject antibiotics at the bottom." In the conference room, Chen Xuhua said in a deep voice.
"Without medication, the death of a patient is a drug-resistant infection. The hospital is not responsible for normal medical risks. If medication is used and the patient dies of drug toxicity, it is a medical malpractice. We are doctors, but we are not saints." One The middle-aged doctor said.
There was a rustling discussion in the conference room, Chen Sufen pursed his lips and did not speak, while Chen Xuhua smiled wryly.
"Then let's vote." Chen Xuhua patted the table, "Raise your hand for those in favor of injections."
There was silence in the conference room. Everyone looked at me and I looked at you, but not a single hand was raised.
"Then I will ask another way and raise my hand in favor of not injecting!"
There was silence again, and a few minutes later, a hand was raised alone, and then it was as if the movie had pressed the play button, and one hand after another was raised.
In the end, except for Chen Xuhua and Chen Sufen who did not express their opinions, almost all doctors opposed the injection of carbapenems to the remaining nine patients.
Chen Xuhua couldn't tell the complexity in his heart, he felt a sense of shame but at the same time heaved a sigh of relief.
"In that case, everyone should do a good job of explaining and reassuring."
"According to our news, last Wednesday, Queen Mary Hospital announced a large-scale nosocomial Pseudomonas aeruginosa infection. The number of people infected this time was 92, of which 78 had successfully escaped the dangerous period, 5 died, and the remaining 8 were still in the hospital. In the process of rescue efforts, this drug-resistant infection is fierce and widespread, and it is very rare in the world. According to the hospital's explanation, this is mainly the result of the abuse of antibiotics. At the same time, the reporter learned from relevant medical practitioners. It is known that in the large-scale Pseudomonas aeruginosa infection, the global average survival rate is less than 12%, and the Queen Mary Hospital achieved 84.8%, which is a miracle!"
"BBC antibiotic abuse topic, British textbooks will put the Queen Mary Hospital incident into the British medical school textbooks!"
"The suspension of the School of Medicine of Hong Kong University is actually related to the Mary patina incident!"
"Another Einstein, the inventor of the original drug discovers a new antibiotic again!"
The reputation of Li Zheng and Li Zheng's laboratory suddenly reached its peak after the internal staff of Queen Mary Hospital accidentally leaked.
"Li Zheng, if this goes on like this, you will have to increase the salary of the security guards. I thought that the paparazzi in Hong Kong were all-pervasive. I didn't expect those reporters from daily newspapers and evening newspapers to jump over the wall." Zheng Lingling said while arranging the experimental table. .
Li Zheng also had a helpless expression on his face. He believed that he had achieved far more achievements in his previous life than he is now. At that time, he never saw reporters blocking the door of his laboratory.
"By the way, didn't you first register the patent this time? You'll save yourself the trouble you did last time."
Li Zheng shook his head.
"It's still a semi-finished product."
Of course, this is just Li Zheng's excuse. Although the carbapenem antibiotics failed the biological test and the drug toxicity is still very strong, the 84.8% survival rate of Queen Mary Hospital can fully explain the practicality of the drug. The molecular structure of the drug is also stable enough to apply for a core patent.
Only Li Zheng knew that at this time, Merck in the United States, also known as Merck & Co., had already registered the core patent for carbapenem antibiotics, and the patent was still in the confidential stage because it involved unmarketed new drugs.
If Li Zheng wants to get a piece of the pie, it's not difficult. After all, Merck's imipenem was only launched globally in 1985. With Li Zheng's foresight, he bypassed the core patent and preemptively registered the generic drug of imipenem. difficulty.
But he wasn't going to do that. As the pride of once the world's top scholars, he is not allowed to do so.
It's just that he thinks so, others don't.
The pursuit of life and health knows no borders. The news that the survival rate of Pseudomonas aeruginosa infection in Hong Kong Mary Hospital was as high as 84.8% soon spread to the United States on the other side of the ocean.
The United States considers itself the country with the most developed medical level, but looking at this miraculous report, Rao, the best expert in the United States, is also stunned.
"The people of Hong Kong must have developed a new antibiotic! God, the antibiotic for Pseudomonas aeruginosa! This is a milestone in the history of antibiotics."
Headquarters of Merck & Co.
Mr. Smith, the president, slammed the New York Daily on his subordinates.
"800 million dollars, a full 800 million dollars, not including laboratory construction and equipment investment! Why are you not as good as a minor child!"
"Mr. Smith, imipenem has reached the biological test stage, and its effect is very good. After seeing the New York Daily, we called the patent offices of various countries as soon as possible, and the biologist named Li Zheng did not Register the carbapenem antibiotic patent." Mr. Brown kept wiping the fine sweat on his forehead.
Imipenem is a key project of Merck, and the first phase of core patent registration was completed seven years ago. However, in the past seven years, drug trials have progressed slowly, and the drug has not been launched for a long time. Seeing that the dawn is just ahead, there is something like Li Zheng. It was like a 3,000-meter long-distance race. He was almost at the finish line, but he found that the first place was already waiting for him at the finish line. This feeling of suffocation is really uncomfortable.
What's more, Merck has invested nearly one billion US dollars for the imipenem project. In the past nine years, if Li Zheng's drug really hit the market first, their loss would be immeasurable.
"Perhaps the scholar did not intend to register the patent..." Mr. Brown's voice was weak.
Smith's cup was slammed to the ground, "Aris Brown, when did you learn to pin your hopes on others. Merck doesn't need such weaklings!"
"Please come over, Mr. Kent. I have something to discuss with him. Also, let the secretary office contact Li Zheng's laboratory. I think I need to talk to that genius in person." Smith said while rubbing his temples.
Brown nodded again and again and quickly walked out of Mr. Smith's office.
A week later, Smith and Kent boarded the plane to Xiangjiang. The British BBC Century People Program Group officially sent an interview invitation letter to Li Zheng's laboratory. The rescue was declared invalid and they died. The three survived with strong willpower, but they left behind lifelong sequelae.
"Teacher, congratulations on being discharged from the hospital!" Li Zheng held a bouquet of carnations and came to pick up Xu Mingsheng to be discharged from the hospital together with the professors of Hong Kong University.
Xu Mingsheng's injury has recovered well. After the operation on his leg, although he is still unable to move freely, it is no problem to walk for a while with a cane every day.
"Hahaha, it's the first time I've received flowers in my long life! Li Zheng, it's really thanks to you this time. You're my savior!" Xu Mingsheng was supported by Chen Sufen and sat on a wheelchair.
"Teacher, you are serious. You have made a good start on this topic. I just follow your ideas and continue to do it."
Xu Mingsheng waved his hand, "Don't humiliate me, thinking... If sorting out information is also thinking, those under me who are studying first and second will be able to take charge of themselves long ago."
Professor Wang laughed, "Old Xu, you should thank Li Zheng, otherwise, your funds would have been split by these old guys long ago."
Xu Mingsheng's eyes bulged when he heard the words, "Go, go! Don't hit me with the idea of funding!"
There was a burst of laughter and laughter in the ward, and while everyone was chatting and laughing, a sudden burst of sadness came from outside the window. Crying, shouting and scolding sounded.
"What happened outside?" Xu Mingsheng asked with a frown.
Chen Sufen stuck her head out to take a look, and the expression on her face suddenly froze.
I saw the entrance of Mary's Hospital. Rows of wreaths blocked the entire entrance of the hospital. Several family members of patients were standing in the center of the entrance with the patient's photo.
They shouted loudly: "Mary's hospital is a waste of life, and no medicine is given!"
The sound of neat slogans accompanies the cry of the woman, girl and child, attracting the attention of passersby.
"Lao Xu, you talk to them, I'll go out first." Chen Sufen said with a strong smile.
Xu Mingsheng patted her hand, "Go, don't worry about me."