"Sorry, sorry." David waved at Pete Smith insincerely, then pulled Li Zheng aside.
"Li, you're crazy!" Carbapenem antibiotics are much more profitable than pamines, and he stretched his arms vigorously to draw a big circle in the air.
Li Zheng looked at David who was constantly gesturing with amusement, and patted him on the shoulder, "Don't worry, I'm not bad for such a patent." The tone seemed to say, I'm not bad for such a dollar.
but! It's not a dollar! It's a patent worth tens of billions!
David looked at Li Zheng up and down, as if he was looking at an alien. Glancing at Smith and the surprise on the affirmative face, he curled his lips and couldn't help but ask again: "Are you serious? If you want, Roche can fully represent you to fight for your rights in carbapenem antibiotics."
"David Andorio!" Smith and Kent, who were listening carefully to Li Zheng's conversation, suddenly raised their hearts. Smith didn't care about cleaning up the residue on his clothes, and strode toward them.
He glared at David, then turned to Li Zheng with a complicated expression, "Mr. Li Zheng, do you mean to give up all rights and interests related to carbapenem antibiotics?"
Hearing this, Li Zheng raised the corners of his mouth slightly, "Mr. Smith, please correct me, I mean that I give up any possibility of obtaining commercial benefits from carbapenems. But this does not mean that I give up the discovery of carbapenems. The identity of one of them."
For Li Zheng, a former top international scholar, fame is much more important than money and interests.
"Of course! This is an indisputable fact!" Smith exclaimed, he was not a scholar, he was just a businessman, and patents and profits were what he valued most.
Smith did not expect to achieve the purpose of his trip so smoothly. The tyrant of Merck did not hesitate to praise Li Zheng from the beginning to the end with the most beautiful compliments. David was stunned when he heard it. This is really true. The indomitable Mr. Smith in his memory?
Smith ignored David's little gesture of winking this time. He took out a thick agreement from his bag with a full smile on his face, "Mr. Li Zheng, according to what you people in Hong Kong say, this mouth is never as good as a pen." Smith said strangely. Strangely, he pulled out a Chinese sentence.
Li Zheng glanced at it, and it was the agreement for him to voluntarily give up the patent rights of carbapenem antibiotics. There are two versions in English and traditional Chinese. It seems that they came prepared.
Li Zheng chuckled lightly, without delaying, took out a pen from his jacket pocket, and simply signed his name neatly at the sign.
Smith's smile was even brighter. He was about to accept the agreement, but Li Zheng smiled and put the agreement on the coffee table and pressed it with a pen.
"I suddenly thought of something and wanted to discuss it with Mr. Smith." Li Zheng said.
Perhaps it is the relationship between the contract templates. There is a line in the agreement that indicates the countries and regions where the first batch of imipenem plans to be listed, such as the United States, Canada, the United Kingdom, France, Italy, and Hong Kong.
There is no China.
Only then did Li Zheng remember that imipenem was first listed in the world in 1985, but it was not until 2007 that Huaguo had the first imipenem cilastatin.
For 22 years, Li Zheng did not know how many Chinese people would have to wait to die in despair because the drug imipenem was not available in China.
"Here, add Huaguo." Li Zheng used a pen to add the word Huaguo after Italy.
Smith and Kent looked at each other, Hua Guo? In the 1980s, the image of China in the hearts of the people of the world was not so good. The country was closed and the economy was backward. In 1979, Premier Deng waved a cowboy hat while watching an equestrian rodeo in Houston, which was interpreted by Western media as a sign that China was opening up and trying to integrate into the world.
A cowboy hat made foreign media so excited, which also reflected from the side how closed and backward the image of China was in the Western world at that time.
"Although China has a large population, their demand for drugs is not large, and the price of imipenem is not cheap for them. I have no reason to persuade the business department to open up such a barren market." Smith said with difficulty.
Li Zheng shook his head, he pushed hard and pushed the agreement in front of Smith and Kent, "Then I'll give you a reason. I..." He pointed to himself, "I'm Chinese. And this Chinese person has the ability to relieve imipenem. methods of nephrotoxicity.”
It took nine years from the registration of the core patent in 1976 to the listing in 1985. If Li Zheng guessed correctly, the Merck drug research team should be stuck on this bottleneck.
"You have a way!" Kent clapped the table and stood up excitedly, "Okay, I promise! As long as the drug is approved for marketing, Huaguo will definitely be one of the first countries to be listed!"
Kent is the head of Merck's research laboratory, and he is also named as the vice president in charge of R&D. Although he generally does not care about things, he has the most voice among the several vice presidents.
Smith's eyes widened. He was about to speak, but Kent stared back at him. The head of the laboratory, Tie Da, the president of Liushui, didn't need to be afraid of Smith as long as there were research results in his laboratory!
Li Zheng guessed right, the launch of imipenem was stuck in clinical trials of the drug. Like the carbapenem antibiotics extracted by Li Zheng, imipenem has severe nephrotoxicity. Even because of this, two drug trial volunteers closed their eyes forever.
For the past nine years, Merck Laboratories has been trying to alleviate renal toxicity. In recent years, it has gained some experience, but it is still far from the strict standards of the US FDA.
After hearing that Li Zheng had successfully extracted carbapenem antibiotics, Kent even had the idea of bribing FDA personnel and hiding the results of biological tests to speed up the marketing of imipenem.
Of course, if imipenem can be successfully marketed through proper channels, that would be the best.
"I'm a little careful. It's up to Dean Chen to contact you about the specific technical cooperation." Li Zheng said with a smile. He doesn't dispute the patent right of imipenem, but the drug improvement technology is always worth a little bit of money.
On Friday night, Li Zheng's interviews with people of the century were broadcast simultaneously on the BBC worldwide.
The indignant people in Hong Kong saw the young man speaking with his eyes lowered on the TV show, and their excitement, which was triggered by the "Three Questions" of Heung Kong Daily, gradually calmed down.
After the anger subsided, reason slowly returned to the cage.
In this case of drug-resistant strain infection, the success of Queen Mary Hospital was praised even by foreign media, but why did their own newspaper in Hong Kong make a fuss about six patients who died of infection
"The risk of unmarketed drugs being used in the clinic, the pressure behind this miracle!"
"Character of the century, a game of life and morality!"
"Trust, the best medicine for doctor-patient conflict!"
On the second day, almost the entire public opinion in Hong Kong was reversed.
"This Li Zheng's influence is really great. Pharaoh called last night and reprinted all the original layouts. The printing house added a 12-hour night shift, and the newspaper almost opened the skylight in the morning." Shen Wannian said, while Put a sliced steak in your mouth.
"Jing La" There was a harsh noise from pouring tea and rubbing the porcelain in the empty restaurant. Yang Wanru's brows furrowed tightly, and she looked at Zhao Qiuhua badly.
Zhao Qiuhua raised his head slightly, his gaze passed through Yang Wanru, and placed it on the TV screen not far away. On the TV screen, that familiar face had a calmness and confidence that she was not familiar with.
"I'm full." Zhao Qiuhua suddenly put down the knife and fork, and the sound of metal and tableware colliding was crisp and powerful.
Shen Hongji glanced at the steak left in Zhao Qiuhua's plate, and said gently, "Eat more, or if you like Chinese food, just let Mrs. Liu cook it."
Zhao Qiuhua shook his head without saying much, nodded to Shen Wannian and Yang Wanru, picked up the jacket on the chair and walked out.
Shen Hongji smiled bitterly, put down the tableware in his hand, and stood up.
"Mom and Dad, I'm full too." After saying that, he put on his coat and quickly chased out.
Yang Wanru was in a hurry, "I'm so pissed off! She really came from a small place, and marrying such an uneducated daughter-in-law is really looking for guilt for me!"
Shen Wannian glanced at her coldly, "When eating, talk less."
Yang Wanru was stagnant, her eyes swept over her daughter who bowed her head to eat and the two empty plates, her dissatisfaction with Zhao Qiuhua reached its peak.
"Qiuhua, wasn't it fine just now? Why are you angry again? I know Mom has a bad temper, but this time..." Shen Hongji's face was helpless.
Shen Hongji and Zhao Qiuhua are college classmates, and the two met in romantic France. At that time, Zhao Qiuhua was bright, full of confidence and vitality. She actively participated in club activities, participated in gatherings of Chinese students, and participated in the feminist movement. When the rest of the people were still stumbling in French, Zhao Qiuhua had mastered English, French, German, and even a small amount of Italian. In the mind of Shen Hongji, who was introverted at the time, Zhao Qiuhua was like a goddess.
Shen Hongji had a crush on Zhao Qiuhua for two years, and with the encouragement of his roommate, he mustered up the courage to confess to the goddess, and Zhao Qiuhua agreed immediately. Only later did Zhao Qiuhua tell him that she had been following him for a long time. Campus love, two-way secret love, the two people's college romance is warm and sincere.
But the happy time always flies very fast. Four years have passed in a hurry. One of the two is going back to Huajing and the other is going back to Xiangjiang. The two made an appointment, and as soon as they got home, they would talk on the phone and announce their love to both parents.
However, Shen Hongji never waited for this call. Later, the political turmoil in Huaguo, the relationship between Xiangjiang and Huaguo was completely cut off, and the two cut off contact.
Until a year ago, when the two met again, Shen Hongji did not hesitate to end his already nominal marriage, and despite Yang Wanru's strong opposition, insisted on obtaining a marriage certificate with Zhao Qiuhua.