Because of the situation that the whole of Africa is about to fall, the World Health Organization also waved its hand and agreed without hesitation to Chen Chen's clinical trial. There was no need to conduct four phases of the experiment, but four phases of trials were combined into one, and only one phase of clinical trials was launched. .
The so-called Phase 1 and Phase 2 here are the testing period of the vaccine. Generally speaking, a vaccine needs to conduct four phases of experiments from development to launch.
The first phase of the trial is mainly to test the safety of the vaccine. The trial can only enroll a few dozen people at most. After these people are injected with the vaccine, they will be observed for several months. The second phase will only be started after confirming that the vaccine will not cause harm to the human body. period trial.
In other words, the first phase of the trial only tests whether it is harmful to people. From the second phase, it starts to test whether the vaccine is effective.
In the third and fourth phases, the number of people began to increase, and the observation time became longer and more rigorous.
It usually takes several years to complete the entire clinical trial, and there are even many vaccines that have not been produced for decades. However, there is also flexibility in this. For example, during the epidemic three years ago, it only took one year for various countries to develop and market vaccines. .
This is related to the global situation. The more violent the virus is, the faster the vaccine development will be.
After all, the number of infections and deaths every day in Africa is over 100,000. Finally, a vaccine will have to go through several years of clinical trials. After the vaccine passes clinical trials, there will be no need to put it on the market, and it will all be burned to compatriots in Africa. Sisters are fine.
Therefore, during this critical period, clinical trials of vaccines must be carried out quickly, and the sooner the better. The World Health Organization has even approved a special indicator that allows such vaccines to cause a small amount of harm to the human body.
In other words, even if the vaccine developed by Chen Chen does some damage to the human body, it is acceptable, as long as it can stop the plague.
As the news of the BE-006 vaccine developed by Life Science City spread to the world, countless people began to focus on Life Science City.
Under Chen Chen's appointment, Professor Bernhard was responsible for the operation of this clinical trial, and the entire Life Sciences City had stopped all experiments, and the entire city's resources were serving this clinical trial.
However, Chen Chen is still very confident about the effectiveness of the vaccine. After all, it is a product based on the research of the entire Hive Laboratory.
You know, Umbrella Company has been studying the Ancestral Virus for thirty years, and has even developed a flower. The genes of the BE-006 virus and the Ancestral Virus are extremely similar. Coupled with the technological level of Hive, this vaccine is almost impossible. There is a possibility of failure.
So, after Chen Chen threw the clinical experiment project to Professor Bernhard, he returned to the Spire Laboratory and began to study the original ancestor virus.
"The ancestor virus has the power to evolve."
At this time, in the Level 4 Biosafety Laboratory of the Minaret Experimental Base, Chen Chen held up a blue test tube and looked thoughtful, "But this evolution is more like a mutation."
As he spoke, he poured the liquid in the test tube into the human cell culture medium, and then observed silently.
At this time, in the laboratory, not only Chen Chen, but also Hannibal and Li Lei's team were present.
Around the laboratory, there are several very complex instruments and equipment. The style of these instruments does not match the other instruments, and they are more like the products of science fiction.
These instruments are the ones that Chen Chen brought from the biohazard plane. With these instruments, the biotechnology of the Spire Laboratory has been enhanced again.
It can even be said that the Minaret Laboratory at this time has exceeded the biological level of modern human civilization and has reached a higher level...
"Mr. Chen."
After a while, Li Lei suddenly called out, "Come and take a look."
After hearing this, Chen Chen walked to the electron microscope and looked at the screen, only to see that the cells in the culture medium began to proliferate rapidly, like bulging bubbles.
"The proliferation rate has changed from a coefficient of 1 to 3, more than twice as much."
Li Lei was vaguely excited, "And every time a cell divides, the length of telomeres hardly decreases. This is exactly the same as the information you brought back. This virus really has the ability to enhance metabolism and extend lifespan." !”
"Don't be too optimistic."
Chen Chen shook his head, without any excitement, "Don't forget, this is just a change that occurs in the most ideal environment of a petri dish. In fact, if it is not in a petri dish, but occurs in the body of a normal person, Inside, I am afraid that this person is already bleeding as if infected with Ebola virus."
"Because of immune system problems?" Li Lei stopped smiling when he heard this.
"Yes, the symptoms are listed in the information."
Chen Chen called up the information on the screen and said, "The ancestor virus contains a superantigen toxin. If this virus really enters the human body, it will definitely attack the human immune system first, including lymphocytes, dendritic cells, and macromolecules. Phagocytosis.”
"And as shown in the culture medium, after this virus infects the human body, it can increase the human metabolism to three times the previous rate. This also means that humans need to consume a lot of nutrients. This consumption rate is simply not what humans can support. Got up."
"So, the ancestor virus has great flaws and does not fit our experiments."
Li Lei nodded with regret.
"However, compared to the original progenitor virus, its advanced products are different."
Chen Chen suddenly changed his words. He squinted his eyes and looked at the leech slices in the petri dish. "If you can fuse part of the leech gene fragment with the ancestor virus, you can get the famous T virus."
"Yes, the T virus is indeed better than the ancestor virus."
Hannibal walked over from the side and added while flipping through the information, "The Ancestral Virus does have the ability to enhance human strength and speed, and can even extend human lifespan, but the price is a very low success rate."
"Just like BE-006, the survival rate after being infected with the ancestor virus is less than 10%, and even if you are lucky enough to survive, your body may not be changed by the ancestor virus, because the human body only produces antibodies and is immune to the virus. It’s just the harm.”
"So the ancestor virus is actually not perfect, it still has huge flaws."
"But the T virus is different. This advanced version of the ancestor virus is different from the virulent virus BE-006, but a mild virus that lives in long-term symbiosis by integrating its own genetic material into the chromosomes of the host cell. "
"During this symbiosis, the host cell's genes are altered due to the integration of the viral chromosome."
As he spoke, Hannibal raised his head and said, "In short, after humans are infected with this virus, genetic recombination will occur."
Hearing this, Li Lei couldn't help frowning and said, "But why did humans infected with the T virus not only fail to evolve, but turned into zombies?"
"That's because evolution failed."
Chen Chen replied, "If you want to cultivate an organism that can truly adapt to the T virus, you must start cultivating it from fertilized eggs. That means you must infect the fertilized eggs with the T virus and let the fertilized eggs grow into real enhanced life forms that can directly infect humans. The only consequence is that evolution fails and turns into a zombie."
"Of course there are exceptions to all this."
After thinking about it, Chen Chen added again, "Maybe one or two lucky people among millions of people can withstand the attack of the virus and become a superman like Alice..."