In the next few days, Chen Chen never left the Minaret Experimental Base.
Chen Chen simply handed over the management of the Life Sciences City to Cheng Chao. Although Cheng Chao didn't know how to manage the city, after all, with the help of Xiao X, nothing would go wrong.
Chen Chen, on the other hand, has been staying in the laboratory, studying the ancestor virus with Hannibal and others.
Because the ancestor virus is not perfect, although it has the ability to evolve life, the probability is extremely low, the fatality rate is extremely high, and its nature is unstable.
They want to upgrade the ancestor virus and transform it into a virus with more stable properties and stronger evolutionary capabilities.
And this road, the Biohazard Plane, has been paved for Chen Chen.
The Umbrella Company spent more than ten years studying the Ancestral Virus, and finally found the brightest path - to fuse part of the Ancestral Virus and leech genes together to form a brand new virus.
As ancient annelids, leeches have excellent environmental tolerance and adaptability, and the transcriptases of the two are homologous. Leech genes can enhance the adaptability of the ancestor virus to the environment, which can improve the stability of the virus.
With all kinds of data obtained from the Hive Laboratory, Chen Chen does not need to make any new attempts. It is enough to use the instruments from the Resident Evil plane and use the method that has been successfully explored for a long time to fuse the two genes together. .
At this time, in the Level 4 laboratory, more than a dozen researchers wearing protective suits were coming and going, constantly busy.
"On the fourth attempt..."
A projector in the center of the laboratory projects images from the microinjector.
In the translucent gel-like petri dish environment, a fixed straw is adsorbing a fist-sized blister. The blister is translucent, and a thin membrane on the outside and various internal components can be faintly seen. Small particles and other strange-shaped substances.
And as the straw adsorbs the water bubbles and slowly moves forward, a transparent needle also appears in the picture.
Then, the two parties came closer, and then the needle gently penetrated the film and penetrated into the blister little by little.
Finally, a few drops of a light blue substance were poured into the bubbles.
Chen Chen silently watched the operations on the screen. Although the picture on the screen looked huge, everything in the picture was smaller than the tip of a needle in reality.
For example, the blister is the fertilized egg of a leech, only a few microns in diameter, and the even smaller ICSI injection needle is only about 0.1 microns in diameter.
Through this infection implantation, coupled with the assistance of some chemical agents, the newly born leeches will have the characteristics of the ancestor virus.
This is a heterophenotypic mosaicism.
After several complex processes such as reproduction, the virus is finally extracted from the leech.
After several failed attempts, the experiment finally succeeded when the genes of the progenitor virus and the leech were completely chimeric together to form a new viral substance.
"It has been extracted, and the genetically recombined virus shows unique properties..."
In the laboratory, Hannibal took out a test tube from the low-speed centrifuge, sucked out all the separated liquid, and poured it into another test tube.
Suddenly, a blue liquid appeared in front of everyone's eyes.
"Don't be too optimistic, let's see the effect first."
Li Lei urged from the side.
"Okay." Hannibal personally walked to the operating table nearby, sucked 0.1 ml of the liquid in the test tube, and at the same time grabbed an SPF-grade white mouse from the breeding cage and injected the virus into it.
"Squeak!"
The little mouse screamed in pain.
However, no one here pitied it. After injecting the virus, Hannibal put the mouse back into the cage, then took out the mice in other cages and injected them one by one.
Hannibal divided these experimental animals into several groups, and each group received different injection doses.
After doing all this, Hannibal looked at the time and said, "It's twenty-two thirty now. According to the information, it will take effect in about three hours."
The assistant on the side quickly pointed an experimental recorder here and recorded the scenes after these mice were infected with the virus.
But at first, the mice injected with the virus seemed perfectly normal and nothing happened.
But as time passed, half an hour later, the mice began to show a trace of anxiety. These mice kept crawling around, as if some natural enemy was threatening it.
As the next hour passed, the mice in each cage began to squeak, and the higher the dose, the more painful they appeared.
After waiting for two hours, the mouse with the highest dose of injection changed from its usual docility and began to hit the wall of the cage with a constant banging sound. However, the mouse itself did not show any signs of pain. .
After waiting for two and a half hours, all the mice showed extremely aggressive behavior and kept hitting the cage, trying to break out of the cage.
But as it bumped and bumped, its movements became slower and slower, and finally it curled up into a ball. It was unclear whether it was dead or fainted.
Three hours later, all the mice woke up again, but this time they returned to their previous state.
"They have survived the virus and have not died or turned into zombies, but have become virus carriers."
Seeing this scene, Li Lei on the side took a breath of air, "Aren't they just like asymptomatic infected people who can spread the virus wherever they go?"
"Yes, that's the horror of this virus."
Chen Chen looked at these mice and said thoughtfully, "The bodies of mice have multiple bacteria and viruses. This has caused the general mice to have resistance that is not inferior to that of bats. Therefore, it is normal for them to become a source of virus infection." …”
"But rats are not representative. We still need to look at other animals."
Chen Chen suddenly thought of the hounds infected with the virus in the movie, and immediately said, "If I guessed correctly, the virus has a different effect on cats, dogs and other creatures."
"Then shall we start animal experiments tomorrow?" Hannibal asked.
Chen Chen pondered for a while, and then said, "Okay, we will start animal experiments tomorrow. How many animals are there in the SPF breeding room now?"
"Currently, there are five types of animals: Kunming mice, SD rats, New Zealand white rabbits, macaques and chimpanzees." the assistant in charge of animal care replied.
"Then let's try the last three tomorrow."
Chen Chen nodded and left the Spire Laboratory.
When he left the laboratory after the complicated disinfection process, Cheng Chao had already received the message and was waiting outside the door, "Boss, do you want to go back to the research center today?"
Chen Chen waved his hand, "I won't leave, but I need you to make a trip. I remember, didn't Walvis Bay Police Station set up its office and prison in Life Sciences City? You go to the police chief and ask him to give it to me. Provide five felons.”
"A serious criminal?"
"Yes, either a murderer or a rapist."
Chen Chen nodded and said, "Then I will ask the Black Knight to cooperate with you to transport these five people in, and I must have one requirement, that is, these people must be in good health."
"I know, I'm going to do it now."
Cheng Chao nodded, turned and left.
The reason why human trials are so soon is because Chen Chen knows that the T virus is actually a virus whose primary target is humans. Although many animals have the ability to carry the virus, the real host of the virus has always been humans. .
It is an accident that a dog turns into a zombie dog after being infected with the virus. In fact, not every animal will be like this.
After watching Cheng Chao leave, he returned to his lounge in the Spire Experimental Base. However, as soon as he lay down on the bed, he felt sleepy, and then he fell into a deep sleep.