Professor Connors has recently been researching a serum that can cure cancer. Almost all animals in the world are susceptible to cancer.
It is just a rumor that sharks cannot get cancer. Although the tumor suppressor factors in cartilage make sharks have a very low chance of getting cancer, they can still get a deadly cancer called melanoma.
Elephants are less likely to get cancer than ordinary animals because the TP53 gene in elephants can detect the integrity of DNA, repair genes that cause cancer cell mutations in a timely manner, and eliminate abnormal cells.
The only animal with a zero cancer incidence is the naked mole-rat. So far, no case of cancer has been found in naked mole-rat.
The naked mole rat genome contains many tumor suppressor genes, such as the arf gene, and lacks genes associated with cancer. The naked mole rat genome has a high copy number of genes responsible for repairing DNA, and the ribosomes can produce proteins with basically zero errors. There are also a large number of molecular chaperone proteins that help other proteins fold correctly. These make the naked mole rat genome and cell state extremely stable.
Secondly, naked mole rat cells contain a hyaluronic acid polymer, which triggers a particularly powerful mechanism, "early contact inhibition", which means that cells stop dividing once they "feel too crowded". Even if cells become cancerous, a few rounds of division will cause cell crowding and trigger this mechanism, and cancer cells will not be able to proliferate wildly.
But Professor Connors was not sure that injecting naked mole rat genes could cure the advanced cancer. Moreover, he was not sure Wade would be able to accept turning into a giant naked mole rat.
After much hesitation, he decided to try to cut out the cancer-suppressing genes from sharks, elephants and naked mole rats and splice them into Wade Wilson's body. If everything went well, Wade would not show the characteristics of those three animals.
This is the original intention of the cross-species gene transplantation project, and the Lizardmen are just a by-product of this project.
The research finally got back on track, and Professor Connors devoted almost all his energy to it, even putting the analysis of the culture medium formula on hold.
If the research is successful, he will almost cure cancer, a terminal disease in humans, from the root.
Because of his countless experiences in preparing serum, Professor Connors made rapid progress. He had already prepared a serum combining three genes and injected it into mice for observation.
After the lessons learned from the Lizard People, he became extremely cautious, fearing that the fusion of animal genes would cause mutations in the human body.
In the first experiment, more than forty out of fifty white mice underwent mutations, with their bodies developing various features of sharks, elephants and naked mole rats. One of them even grew seven or eight hands and feet and more than a dozen pairs of eyes, which was so strange and eerie that it made people shudder.
Even though Professor Connors was a master of biology and had dissected countless samples, he was still disgusted by these mutated test subjects.
After destroying the failed products, he analyzed those test subjects that luckily did not mutate, deleted the genomes that might cause the main body to mutate, and improved the formula of the serum.
However, the workload of this project was extremely large, and he was alone without any assistants, so the progress was slow and it would take a long time.
Professor Connors felt overwhelmed when he thought of the huge amount of data stored in the computer. If he hadn't been injected with lizard serum, he might have been bald by now.
Suddenly someone rang the doorbell of the laboratory. Connors took a look and found that it was Broly outside, so he hurriedly opened the door of the laboratory.
He felt a little uneasy because the two projects Broly had assigned to him had hit a bottleneck and were progressing slowly.
Broly glanced around the lab and placed the cooler in his hand on the ground.
"This is a sample of cancer cells from Wade's body."
When Professor Connors heard that he had obtained the samples, he immediately became interested. These cancer cells cut from Wade's body could be placed in the culture medium to multiply. When the formula of the serum is successfully debugged, it can be used to test whether it can effectively restrain cancer cells.
“These cancer cells are not ordinary.”
Broly shook his head and described the abnormalities in Wade's body during the operation.
Professor Connors was shocked. Because of his research on serum, he had read a lot of information and papers about cancer in this short period of time, but it was also the first time he saw such a strange cancer.
With a hint of curiosity in his heart, he immediately opened the refrigerator, took out the frozen tumor inside, sliced it, and placed it under the electron cryo-microscope stolen from the Osborne Group.
Under a microscope that is powerful enough to see macromolecular structures, cancer cell samples are clearly visible.
"How is it possible... that so many cancer cells are still active?"
Professor Connors couldn't help but exclaim. Under the microscope, about 60% to 70% of the cancer cells were still very active, constantly wriggling and devouring each other.
Cancer cells are very difficult to deal with in the human body. It can be said that they can be reborn even if a wildfire burns them out. But once they are exposed to the external environment, they will become very fragile and difficult to survive. He wanted to cultivate cancer cells in order to multiply the very small number of cells that might survive in the tumor.
Broly raised his eyebrows and looked at the tumor in the freezer. The aura of the tumor was so weak that it was almost undetectable, so he didn't know that most of the cancer cells inside were still alive.
"interesting."
A large ball of energy immediately gathered in his hands, and the dazzling light almost blinded Professor Connors temporarily.
Broly threw the extremely powerful Qi into the refrigerator and merged into the cancer cells. He wanted to see what changes would occur if the cancer cells absorbed a large amount of Qi.
The large mass of air was not painful to Broly, but to the cancer cells, it was like mice entering a granary. They stopped devouring each other and began to swallow air frantically.
The entire tumor, which looked completely dead, suddenly seemed to come alive, wriggling and proliferating rapidly. Clusters of hideous blisters filled with yellow-green pus and blood appeared on the surface of the tumor, interconnected, and rapidly expanded in size. Within just a few minutes, the entire tumor expanded three or four times its size, filling the entire refrigerator.
Countless tentacle-like tentacles kept swaying, making the refrigerator crackle.
Broly could even sense that the energy of the entire tumor was rising rapidly. In this short period of time, it was already almost the same as that of an ordinary person and was still getting stronger.