Polyester is the first material used in the manufacture of artificial blood vessels. Medical polyester, like medical sutures, has been tested for its long-term safety in the human body. Its biggest problem is that the anticoagulant is not good, it needs anticoagulant pretreatment, and it needs to be coated with biological coating.
ePTFE is the expansion body of PTFE, commonly known as the king of plastics, which is equivalent to a new product based on PTFE and made with a special process. In contrast, ePTFE performs very well in terms of anticoagulant properties, and has good biocompatibility in the human body. The rejection reaction is very light, and it is also not easy to degrade like polyester. It can be used in the human body for a long time without frequent replacement. . Compared with polyester, there is no need for anticoagulation pretreatment, no biological coating, all these conveniences make it widely acclaimed clinically.
Does the new generation of artificial blood vessel star materials really have no shortcomings at all? Nothing in the world is safe and perfect. It is impossible for medical devices to be the same as the human body's own long tissues and organs.
The shortcomings of ePTFE have been summarized in international research papers. It is always inferior to the elasticity of the human body's own blood vessels. The softness is somewhat inferior to that of the human body, which causes blood to flow in it for a long time, and it is easier to form at the anastomosis over time. A blood clot causes a blockage.
Such device materials are a test of the surgeon's technical level.
If a surgeon is highly skilled, he may be able to help the patient handle the artificial vascular anastomosis better, and the probability of blockage is low, even if it will delay the time point. If the surgeon's skills are so-so, the consequences needless to say.
Is it possible to require surgeons to be highly skilled
impossible. There has always been an imbalance between the supply and demand of exceptionally good surgeons.
It’s like inventing a smartphone. It must have enough foolish operation methods for most people to use it immediately. If it is made into a complicated operation that only coders can use, it will become something that is not for the public. It can't be sold.
In the medical material market, it becomes: the created medical and surgical materials must meet the technical level of most surgeons, not the technical level of big cattle.
If we simply use Daniel's technical level to make medical equipment, we will not be able to promote it, and we will not even be able to pass the clinical trials, because the results of the clinical trials will be so bad that they will be a mess. For example, there is one clinical trial indicator for artificial blood vessels, called the long-term vascular patency rate. The operation performed by Daniel may make this material perform excellently in this index, reaching 80 to 90% after half a year, while surgeons with ordinary skills can only reach 40 to 50% unqualified.
The test results should be based on surgeons with general technical skills. Seeing this clinical test value, all clinicians and researchers will become two big.
To sum up, ePTFE has its shortcomings, but since it has been affirmed in the production of artificial blood vessels in the world. Again, the bad ratio should be controlled within a controllable range and should not exceed it.
Then it just becomes a matter of choice. Or is this material not good enough? Or there is an indescribable contradiction between this surgical technique and the new product
The teachers at the conference table had solemn expressions and asked each other. First determine whether these problematic cases are widely present in various hospitals.