“You want to work on custom vaccine technology?”
In the conference room of the institute, Chen Mo's words made Shi Hongtu and other expert members look surprised. Only Wu Bing was relatively calm. When she learned Chen Mo's thoughts on the road just now, she was a little surprised.
"Yes." Chen Mo nodded.
Last night, I carefully digested the technical information of "Customized Vaccine System" and I already have a general idea in my mind.
"Many medical scientists are studying customized vaccine technology, but no one can guarantee when it will be successful. We don't have that much time to study this technology now," Shi Hongtu said.
Including Wu Bing, other expert groups agreed with Shi Hongtu's words.
The concept of customized vaccine technology has long been proposed, and some research progress has been made. However, in the medical field, customized vaccines are still at the stage of trying to cross the river by feeling for stones. It is somewhat inappropriate to use it in such an emergency virus incident.
They only have one month now, and the efficacy of the improved HX3 drug can probably delay the epidemic for a month. A month later, for the first batch of people who use the improved HX3 medicine, the medicine loses its effect and a steady stream of deaths will occur.
"This is the direction I am most sure of succeeding in," Chen Mo said.
Everyone on the field had strange expressions, and Shi Hongtu's eyelids even twitched. Customized vaccine technology can be said to be one of the most difficult topics in all current research on specific drugs. What is Chen Mo's most confident direction now? I have to say that Chen Mo's idea is a bit different.
"We don't have much time," one panelist said.
"What do you mean there is not much time? Who can determine which kind of research will take the shortest time? Do you want to develop a specific drug within a month? Don't you know this kind of research? Maybe tomorrow a team will announce that it has found a specific drug, maybe Even if the entire human race becomes extinct, it will not be found.”
Chen Mo's question made everyone on the court quiet and a little embarrassed. They want to treat patients quickly, but they ignore that they are doing research now.
Those who are engaged in research all know that when studying this kind of thing, it may suddenly succeed tomorrow, or it may not succeed until they are in the coffin. It mainly depends on whether the researchers can find the node for technological breakthrough.
If you can't find the key, no matter how much time you give, it will be in vain. If you can find it, the road ahead will be smooth.
"Customized vaccine technology is not yet mature, and the research and development speed may be slower than other agents." A gray-haired expert said: "Why don't you continue to study HX3, Academician Chen? The improved HX3 agent has successfully suppressed the Reedman virus. Improvements may not eliminate the virus.”
This remark caused other medical experts to nod.
The improved HX3 agent has achieved good results, at least it is effective against Reedman virus. This is a definite direction.
"HX3 is just a protease inhibitor. Its effect is limited to inhibiting the replication of viral proteins and allowing the virus to enter a dormant phase. It cannot inactivate the virus itself, otherwise its function is not to reduce viral activity. If it can really clear the virus, it will My first improvement direction was not to inhibit its metabolism," Chen Mo said.
HX3 was developed by Haixing Company with the information he provided. He knew all its functions and effects clearly. No matter how it was modified, its function was to reduce the activity of the virus, and its essence could not be changed.
"But customized vaccine technology, this technology is full of too many uncertainties."
"Have you determined the research direction for specific drugs for Reedmann virus? Which direction is correct?" Chen Mo asked.
All the researchers present were breathless and unable to answer.
"Have you really decided to research a customized vaccine?" Shi Hongtu asked.
He is the leader of the medical team, and his main task is to find a specific drug against Reedman virus as soon as possible. Although he does not agree with Chen Mo's research on customized vaccines, he cannot influence Chen Mo's ideas.
"Yes." Chen Mo nodded.
The scene fell into silence again, and they had no good solution to Chen Mo's persistence.
"Let me tell you what I think."
Wu Bing spoke, and everyone on the field looked at her. As one of the youngest researchers in the medical team, Wu Bing's ability is no less than that of others, so his words still carry weight.
"Academician Chen formed an independent group to study customized vaccine technology, and others studied reverse enzyme inhibitors. This way, he was divided into two groups and worked hand in hand. At least there was one more possibility in the choice to avoid a dead end."
Shi Hongtu sighed. Judging from Chen Mo's attitude, it was impossible to give up the research direction of customized antibodies. No matter how much they said, it would be useless. Chen Mo has the right to freely choose any direction of research without restrictions. This is what Chen Mo said when he joined the group.
Now Chen Mo is just informing them, not asking for their opinions.
"Since Academician Chen insists, as Academician Wu said, the team led by Academician Chen will study customized vaccine technology, and the others will study reverse enzyme inhibitors according to the original research plan."
Shi Hongtu finally came to a conclusion.
"Who is willing to join Academician Chen's group to study customized vaccine technology?"
Many experts on the scene did not say anything. Customized vaccines are being studied in peacetime. If they come out, this will be a vaccine technology that transcends the times. But now during the virus outbreak, this is not a good option.
"As before, my team and I will join Academician Chen's group to conduct research," Wu Bing said.
Chen Mo was not surprised by this situation. As expected, he just nodded slightly to Wu Bing.
"Okay, today's meeting is over. Everyone will continue to carry out research. Any progress will be reported immediately for discussion. The current epidemic situation outside is not optimistic."
Shi Hongtu's last sentence made the atmosphere heavy.
…
In a small office at the institute, six researchers sat quietly.
The six people are members of Wu Bing's team, four men and two women. They all look young, around thirty years old. They are the team with the lowest average age among the medical team. They are all outstanding students of the Academy of Medicine, or members of the medical research project team. The minimum academic qualification is a doctor of medicine.
Chen Mo and Wu Bing were also in the laboratory at this time, and Chen Mo had some documents in his hand.
"Now I will assign you your own research tasks. The topic of our group is customized vaccine technology. This topic is a bit difficult. If you want to speed up the research and development, you must cooperate with me in the research."
Chen Mo spoke, and everyone cheered up. Although Chen Mo did not graduate from a medical school, from the beginning of the VFV virus to the success of the improved HX3 drug, he has proven his strength in drug research, enough to be a mentor for any of them.
"You are divided into two groups. The first group, together with Academician Wu, is responsible for isolating the protective antigen gene of the virus and determining the gene sequence. The second group will work with me to build a system platform for customized vaccines. This is your project information. "
Chen Mo handed the information in his hand to several people.
"This is an epoch-making technology. If it is successful, it will have a revolutionary effect on the medical field. Medical scientists can quickly produce infectious disease vaccines for certain diseases, or even mixed vaccines carrying multiple antigens."
The six people were awe-inspiring, and their hearts were burning for a moment.
The country is not the hardest hit area and is relatively calm. But the international medical community is not calm. Almost all famous immunology doctors have been summoned to set up a specialized research team.
The improved HX3 agent treats the symptoms but not the root cause.
The patients have special conditions, such as patients with severe schizophrenia, and they are also contagious. Countries in the hardest-hit areas are under unprecedented pressure.
Medical facilities and anti-epidemic supplies are in urgent need across the board.
Protective clothing, masks, and gloves are all disinfected before use and reused. The risk of infection among some medical staff is increasing. In some of the most serious countries, due to the extreme lack of medical facilities, patients have been detained in an isolation area and controlled by military chemical defense forces.
Now using HX3 medicine, the patient regains consciousness and management is relatively simple. But a month later, the backlog of patients has not been cured, the medicine has failed, and the medical facilities are insufficient. When the patient loses consciousness again, no one knows what the consequences will be.
As time goes by, there is no good news about breakthroughs in specific drugs in the medical community. Those on the frontline of the medical fight began to feel a shadow cast over their hearts. Because the first batch of patients using the improved HX3 agent will soon face the consequences of drug failure.
(End of chapter)