"Yeah, I remember that major depressive disorder is a very serious mental illness. It is said to be caused by a combination of genetic and environmental factors, and stress is the main environmental risk factor." Ringer was also skeptical. I simply don’t believe in Dr. Lancer Payne’s views and treatment.
"There is still a principle." Although Zheng Ren does not believe that fecal transplantation can treat severe depression, he still tells the truth, "More and more evidence shows that the microbiome is an environmental factor that can be treated through the microbiome-intestine- Brain axes shape the brain, and mice with altered microbiomes often exhibit depression-related behaviors."
"It is said to be related to the NLRP3 gene." Su Yun added.
"What N?" Lin Ge was stunned.
"Uh..." Zheng Ren found that it was really difficult to explain clearly. He thought for a while and said: "To put it simply, it is to knock out NLRP3... a kind of mouse that has been knocked out of a gene related to depression. The stool is made into capsules and given to patients orally.”
“…”
Lin Ge and Director Kong were stunned.
Although I have experienced many battles, I feel disgusting when I think about Huanglong soup and rat feces. Nowadays, we still have to take the feces of mice orally. Can this really cure diseases
"Director Lin, what's that expression on your face?" Su Yun felt happy and looked at Lin Ge pretending to be serious, "Do you eat rat droppings? This has been around since ancient times."
"I do know that there is a snack for children called rat droppings. My friends from Jinling still look for it all over the world during New Years and holidays. Unfortunately, the sales are becoming less and less."
"The snacks you are talking about are made from tangerine peel, plum blossoms, white sugar, and hawthorn." Su Yun chuckled and said, "You show your age with just one sentence. Who in this age still eats rat shit."
"Memories, memories."
"There is rat droppings in Chinese medicine, did you know?" Su Yun brought the topic back up like a prank.
"Wulingzhi is the feces of the compound-toothed flying squirrel." Zheng Ren said, "It is mainly used to treat cold air in the heart, five malnutrition in children, ward off epidemics, treat intestinal wind, unblock the qi and pulse, and close the moon in women."
"It's unprofessional for you to say that..."
"As long as you know what it means, why are you so professional?" Zheng Rendao, "Using fecal transplantation to treat severe depression is still in the animal experiment stage, and I am not optimistic about this kind of animal experiment."
"Just because we can't tell whether the mice are really depressed? In fact, we can still tell through activities, communication, and play." Seeing that Zheng Ren didn't want to talk, Su Yun smiled and went over, continuing to talk about treating depression.
"To treat Clostridium difficile infection, fecal transplantation can be tried, but the risk is extremely high." Zheng Rendao, "But..."
"Stop talking nonsense. They hired American experts to treat me. Do you believe it or not that you just denied it so carelessly that Director Mao's family just kicked you out?" Su Yun blew, his forehead darkened. The hair is fluttering.
"Not that much."
"What's wrong? I heard that Director Mao is currently in the stage of illness. No matter who he sees, he grabs his hands and says sorry. His memory is very good, and he can talk about every little detail for a long time." Su Yundao.
"Oh? You think your life is worthless, you feel extreme guilt, regret, helplessness, despair and self-abasement. These points are quite consistent with major depressive disorder." Zheng Ren said: "If that's the case, it's okay. good idea."
When Lin Ge heard what Zheng Ren said, he lowered his head and sighed.
"Tch, are you talking about the DSM-IV-TR diagnostic criteria or the ICD-10 diagnostic criteria?"
"No." Zheng Ren had no intention of quarreling with Su Yun today. He said directly: "I still agree with Director Mei, normal drug treatment. Fecal transplantation, whether it is intestinal or oral capsules , may cause more and bigger problems.”
"Okay, Boss Zheng, I will reflect your views to the hospital." Lin Ge finally said cautiously.
"Regarding fecal transplantation, there have been many new research findings recently. For example, in a study in the journal "Cell" in August 2019, Erick Riquelme and Florencia McAllister of the Anderson Cancer Center in the United States found that a small number of long-term survival pancreatic cancer patients, tumors The microbes are significantly more diverse."
"Can fecal transplantation cure cancer?" Ringer was surprised.
"It's just a discovery. Whether it works or not requires long-term research." Zheng Rendao: "It may be a wrong direction. Fecal transplantation is a good thing, but I don't think the experimental method should be used in clinical practice."
"good."
Lin Ge nodded, then stood up and said: "Boss Zheng, let me report to the courtyard."
"Director Lin, she said that after Director Mao confessed to her husband, her husband was angry for an hour, then slammed the door and left. Is this true?" Su Yun continued to gossip.
Ringer smiled bitterly.
"Why are you asking so many questions? It has nothing to do with diagnosis or treatment." Zheng Ren said.
After hearing what Zheng Ren said, Lin Ge smiled apologetically, turned and left.
Zheng Ren then said a few words to Director Kong and left the office.
"Boss, do you really think fecal transplantation is unreliable?" Su Yun asked.
"It's not unreliable, but it takes a long time to study. The treatment of Clostridium difficile has been used clinically, but the mortality rate is very high."
"If you don't use it, the mortality rate will be nearly 100%." Su Yun shot back.
"Who knows, medical treatment has nothing to do with us." Zheng Ren didn't want to think about it. Being a surgeon was enough.
"Boss, the interventional discipline belongs to the imaging major and is a clinical auxiliary discipline." Su Yun was too talkative and misinterpreted the meaning, directly attacking Zheng Ren's weakness.
Zheng Ren was too lazy to pay attention to this guy and returned to the office to continue reading.
This time he was looking for information about fecal transplantation.
It will take twenty or thirty years for fecal transplantation to become a routine clinical treatment.
Zheng Ren just saw it fresh and didn't want to study it from beginning to end. Even though the skill Eye of Truth has cooled down, Zheng Ren doesn't want to use it.
Who knows the scope behind a study, but if you use it casually, you may drain your energy and faint to death.
Zheng Ren has to learn to be good once he suffers a loss. The eye of truth cannot be used casually. The gastric fundus and left gastric artery embolization surgery can be seen at a glance. Is it simple after all
As for fecal transplants…
As an emerging treatment method, it covers a wide range of categories. It seems to be found in treating dysbiosis, treating depression, treating cancer, and treating diabetes.
There was a lot of information, and the more Zheng Ren looked at it, the more he gave up the idea of using his true eyes to find out. It's so majestic that if you take a look at it, you won't faint to death, but actually die.